Standardized Treatment of Pulmonary Exacerbations II
Public ClinicalTrials.gov record NCT02781610. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
Standardized Treatment of Pulmonary Exacerbations II (STOP2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Cystic fibrosis (CF), a life-shortening genetic disease, is marked by acute episodes during which symptoms of lung infection increase and lung function decreases. These pulmonary exacerbations are treated with varying antibiotics for varying time periods based on needs determined by individual patients, their families, and the health care providers. Cystic fibrosis pulmonary guidelines for the treatment of pulmonary exacerbation published by the Cystic Fibrosis Foundation (CFF) in 2009 provided recommendations for treatment and also identified key questions for which additional studies were needed. A strong desire among clinicians to reduce treatment durations (and reduce cost, inconvenience, and potential toxicities) is in conflict with belief that patients not responding robustly to treatment might benefit from extending treatment. This randomized, controlled, open-label study is designed to evaluate the efficacy and safety of differing durations of IV treatment, given in the hospital or at home for a pulmonary exacerbation in adult patients with CF.
Study identification
- NCT ID
- NCT02781610
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 982 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2016 (Type not available)
- Primary completion
- Mar 6, 2020 (Actual)
- Completion
- Mar 6, 2020 (Actual)
- Last update posted
- May 19, 2021
2016 – 2020
United States locations
- U.S. sites
- 57
- U.S. states
- 30
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Children's Hospital Alabama | Birmingham | Alabama | 35233 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99519-6604 | — |
| University Medical Center | Tucson | Arizona | 85724 | — |
| UC San Diego Medical Center | La Jolla | California | 92037 | — |
| Lucile S. Packard Children's Hospital | Palo Alto | California | 94304 | — |
| University of California Davis, Health System | Sacramento | California | 95817 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| Shands Hospital | Gainesville | Florida | 32610 | — |
| Joe DiMaggio Children's Hospital (Adult) | Hollywood | Florida | 33021 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| St. Luke's Regional Medical Center | Boise | Idaho | 83712 | — |
| Saint Francis Medical Center | Peoria | Illinois | 61603 | — |
| Indiana University Hospital, Indiana University Health | Indianapolis | Indiana | 46202 | — |
| The University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| John Hopkins Hospital | Baltimore | Maryland | 21205 | — |
| Boston Children's Hospital (BCH) | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Health Care (Worcester, MA) | Worcester | Massachusetts | 01655 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5212 | — |
| Detroit Medical Center; Harper University Hospital | Detroit | Michigan | 48201 | — |
| Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| St. Louis Washington University Adult - Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Billings Clinic | Billings | Montana | 59107-7000 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Robert Wood Johnson University Hospital (New Brunswick, NJ) | New Brunswick | New Jersey | 08903 | — |
| Women and Children's Hospital of Buffalo | Buffalo | New York | 14222 | — |
| The Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Highland Hospital; Strong Memorial Hospital | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| North Carolina Children's Hospital | Chapel Hill | North Carolina | 27517 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Akron Children's Hospital | Akron | Ohio | 44308 | — |
| University Hospital of Cleveland | Cleveland | Ohio | 44106 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Dayton Children's Hospital | Dayton | Ohio | 45404 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| Medical University of South Carolina; Medical University of South Carolina Children's Hospital | Charleston | South Carolina | 29425 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| Baylor St. Lukes Medical Center | Houston | Texas | 77030 | — |
| University of Texas Health Center at Tyler | Tyler | Texas | 75708-3154 | — |
| The University of Vermont Medical Center Inc. | Burlington | Vermont | 05401 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Medical College of Virginia (Richmond, VA) | Richmond | Virginia | 23298 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Ruby Memorial Hospital | Morgantown | West Virginia | 26506 | — |
| University of Wisconsin Hospital Center | Madison | Wisconsin | 53792 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02781610, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2021 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02781610 live on ClinicalTrials.gov.