Volixibat (SHP626) in the Treatment of Adults With Nonalcoholic Steatohepatitis (NASH)
Public ClinicalTrials.gov record NCT02787304. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Double-blind, Randomized, Placebo-controlled, Dose-finding Study to Evaluate the Safety, Tolerability and Efficacy of Volixibat Potassium, an Apical Sodium-Dependent Bile Acid Transporter Inhibitor (ASBTi) in Adults With Nonalcoholic Steatohepatitis (NASH)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if the investigational treatment volixibat (SHP626) is safe, tolerable and effective in adults with nonalcoholic steatohepatitis (NASH).
Study identification
- NCT ID
- NCT02787304
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 197 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 24, 2016 (Actual)
- Primary completion
- Jul 27, 2018 (Actual)
- Completion
- Jul 27, 2018 (Actual)
- Last update posted
- Nov 25, 2019
2016 – 2018
United States locations
- U.S. sites
- 49
- U.S. states
- 25
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern California Research Center | Coronado | California | 92118 | — |
| Fresno Clinical Research Center | Fresno | California | 93720 | — |
| Ceders-Sinai Medical Center | Los Angeles | California | 90048 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| South Denver Gastroenterology, PC | Englewood | Colorado | 80113 | — |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| George Washington (GW) Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| Schiff Center for Liver Diseases | Miami | Florida | 33136 | — |
| South Florida Center of Gastroenterology | Wellington | Florida | 33414 | — |
| Internal Medicine Associates of Wellstar Atlanta Medical | Atlanta | Georgia | 30312 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Gastrointestinal Specialists of Georgia | Marietta | Georgia | 30060 | — |
| The Queen's Medical Center - Liver Center | Honolulu | Hawaii | 96813 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Liver Research Center | Louisville | Kentucky | 40202 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Digestive Disease Associates | Catonsville | Maryland | 21228 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01605 | — |
| Henry Ford Health System | Novi | Michigan | 48377 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64157 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Northwell Health Inc. | Manhasset | New York | 11030 | — |
| Concorde Medical Group PLLC | New York | New York | 10016 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Center for Liver Disease | Charlotte | North Carolina | 28204 | — |
| DUMC-Gastroenterology | Durham | North Carolina | 27710 | — |
| Cumberland Research Associates, LLC | Fayetteville | North Carolina | 28304 | — |
| Carolinas Center for Liver Disease | Statesville | North Carolina | 28677 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Clinsearch, LLC | Chattanooga | Tennessee | 37421 | — |
| University of TN Health Science Center | Memphis | Tennessee | 038104 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| Austin Center for Clinical Research | Austin | Texas | 78756 | — |
| Methodist Health Systems Clinical | Dallas | Texas | 75203 | — |
| Baylor College of Medicine - Advanced Liver Therapies | Houston | Texas | 77030 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| DHAT Research Institute | Richardson | Texas | 75082 | — |
| UVM Medical Center | Burlington | Vermont | 05401 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| Bon Secours Liver Institute of Virginia | Richmond | Virginia | 23226 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| UW Digestive Health Center (DHC) | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02787304, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 25, 2019 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02787304 live on ClinicalTrials.gov.