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Completed Phase 3 Interventional Results available

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

ClinicalTrials.gov ID: NCT02798471

Public ClinicalTrials.gov record NCT02798471. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 9:49 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-label, Randomized, Multi-center, Controlled Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of Edoxaban and to Compare the Efficacy and Safety of Edoxaban With Standard of Care Anticoagulant Therapy in Pediatric Subjects From Birth to Less Than 18 Years of Age With Confirmed Venous Thromboembolism (VTE)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in pediatric subjects with confirmed VTE.

Study identification

NCT ID
NCT02798471
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Daiichi Sankyo
Industry
Enrollment
290 participants

Conditions and interventions

Eligibility (public fields only)

Age range
1 Day to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 26, 2017
Primary completion
May 23, 2022
Completion
May 23, 2022
Last update posted
Feb 27, 2025

2017 – 2022

United States locations

U.S. sites
22
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Banner University Medical Center Tucson Arizona 85724
Children's Hospital Los Angeles Los Angeles California 90027
UCLA Medical Center CAR Los Angeles California 90095
Stanford University Medical Center Stanford California 94305
University of Miami Miller School of Medicine Miami Florida 33136
University of South Florida Tampa Florida 33606
Rush University Medical Center Chicago Illinois 60612
Advocate Children's Hospital-Oak Lawn Oak Lawn Illinois 60453
Indiana Hemophilia and Thrombosis Center Indianapolis Indiana 46260
University of Louisville Louisville Kentucky 40202
Spectrum Health Helen DeVos Children's Hospital Grand Rapids Grand Rapids Michigan 49503
Children's Hospital & Clinics of Minnesota Minneapolis Minnesota 55404
Washington University School of Medicine St Louis Missouri 63110
University North Carolina- Chapel Hill Chapel Hill North Carolina 27517
Levine Children's Hospital Charlotte Charlotte North Carolina 28204
The Presbyterian Hospital Charlotte North Carolina 28210
East Carolina University Greenville North Carolina 27858
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Hasbro Children's Hospital Providence Rhode Island 02903
Le Bonheur Childrens Hospital Memphis Tennessee 38105
St. Jude Children's Research Hospital Memphis Tennessee 38105
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 118 non-U.S. sites.

Recently updated Venous Thromboembolism (VTE) trials

Other public records listing Venous Thromboembolism (VTE). Sorted by last update posted; newest first. Not a recommendation.

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About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02798471, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 27, 2025 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02798471 live on ClinicalTrials.gov.

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