Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults
Public ClinicalTrials.gov record NCT02840474. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
VRC 607-ACTG A5378: A Phase 1, Single Dose Study of the Safety and Virologic Effect of an HIV-1 Specific Broadly Neutralizing Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS) or VRC-HIVMAB075-00-AB (VRC07-523LS), Administered Intravenously to HIV-Infected Adults.
Study identification
- NCT ID
- NCT02840474
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 16 participants
Conditions and interventions
Conditions
Interventions
- VRC-HIVMAB075-00-AB Biological
- VRC-HIVMAB080-00-AB Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 23, 2017
- Primary completion
- Jan 14, 2020
- Completion
- Jan 14, 2020
- Last update posted
- Jan 29, 2025
2017 – 2020
United States locations
- U.S. sites
- 6
- U.S. states
- 5
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama HIV Clinic Clinical Research Site, AIDS Clinical Trials Group (ACTG) | Birmingham | Alabama | 35294 | — |
| UCLA CARE Center, AIDS Clinical Trials Group (ACTG) | Los Angeles | California | 90035 | — |
| Washington University Therapeutics, AIDS Clinical Trials Group (ACTG) | St Louis | Missouri | 63110 | — |
| University of Cincinnati University Hospital, AIDS Clinical Trials Group (ACTG) | Cincinnati | Ohio | 45267 | — |
| Ohio State University Clinical Research Site, AIDS Clinical Trials Group (ACTG) | Columbus | Ohio | 43210 | — |
| Hospital of the University of Pennsylvania Clinical Research Site, AIDS Clinical Trials Group (ACTG) | Philadelphia | Pennsylvania | 19104-6056 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02840474, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 29, 2025 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02840474 live on ClinicalTrials.gov.