Efficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral Atogepant (AGN-241689) in Episodic Migraine Prevention
Public ClinicalTrials.gov record NCT02848326. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel-Group Study To Evaluate The Efficacy, Safety, And Tolerability Of Multiple Dosing Regimens Of Oral AGN-241689 In Episodic Migraine Prevention
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety and tolerability of the following doses of atogepant (AGN-241689): 10 mg once daily (QD), 30 mg QD, 30 mg twice daily (BID), 60 mg QD, and 60 mg BID for the prevention of episodic migraine and will characterize the dose/response relationship.
Study identification
- NCT ID
- NCT02848326
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 834 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 6, 2016 (Actual)
- Primary completion
- Apr 2, 2018 (Actual)
- Completion
- Apr 23, 2018 (Actual)
- Last update posted
- Dec 6, 2018
2016 – 2018
United States locations
- U.S. sites
- 75
- U.S. states
- 30
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Achieve Clinical Research | Birmingham | Alabama | 35216 | — |
| Radiant Research, Inc. | Chandler | Arizona | 85224 | — |
| The Research Center of Southern California, LLC | Carlsbad | California | 92011 | — |
| Neuro-Pain Medical Center, Inc | Fresno | California | 93710 | — |
| Irvine Center for Clinical Research | Irvine | California | 92618 | — |
| Downtown LA Research Center, Inc. | Los Angeles | California | 90017 | — |
| Excell Research | Oceanside | California | 92056 | — |
| Artemis Institute for Clinical Research | San Marcos | California | 92078 | — |
| Diablo Clinical Research Inc | Walnut Creek | California | 94598 | — |
| Advanced Neurosciences Research | Fort Collins | Colorado | 80528 | — |
| Hartford Headache Center | East Hartford | Connecticut | 06118 | — |
| Associated Neurologists of Southern Connecticut, P. C. | Fairfield | Connecticut | 06824 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| The George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Clinical Research South Florida | Coral Gables | Florida | 33134 | — |
| Infinity Clinical Research | Hollywood | Florida | 33021 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Clinical Neuroscience Solutions Inc | Jacksonville | Florida | 32256 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| Suncoast Research | Miami | Florida | 33135 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Clinical Neuroscience Solutions | Orlando | Florida | 32801 | — |
| Palm Beach Neurological Center / Advanced Research Consultants, Inc. | Palm Beach Gardens | Florida | 33410 | — |
| Suncoast Neuroscience Associates, Inc. | St. Petersburg | Florida | 33713 | — |
| Infinity Clinical Research LLC | Sunrise | Florida | 33351 | — |
| Meridien Research | Tampa | Florida | 33634 | — |
| Neurology Research Institute Palm Beach | West Palm Beach | Florida | 33407 | — |
| Institute for Advanced Medical Research | Alpharetta | Georgia | 30005 | — |
| Radiant Research | Atlanta | Georgia | 30328 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta, LLC | Decatur | Georgia | 30030 | — |
| Pediatric and Adolescent NeuroDevelopmental Associates (PANDA) Neurology | Sandy Springs | Georgia | 30328 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Northwest Clinical Trials, Inc. | Boise | Idaho | 83704 | — |
| Healthcare Research Network II, LLC | Blue Island | Illinois | 60406 | — |
| Rowe Neurology Institute | Lenexa | Kansas | 66214 | — |
| Boston Clinical Trials Inc | Boston | Massachusetts | 02131 | — |
| Northeast Medical Research Associates, Inc. | North Dartmouth | Massachusetts | 02747 | — |
| Medvadis Research Corporation | Watertown | Massachusetts | 02472 | — |
| New England Regional Headache Center | Worcester | Massachusetts | 01605 | — |
| Michigan Head Pain and Neurological Institute | Ann Arbor | Michigan | 48104 | — |
| Clinical Research Institute, Inc. | Minneapolis | Minnesota | 55402 | — |
| Mercy Research | Springfield | Missouri | 65806 | — |
| Clinvest | Springfield | Missouri | 65807 | — |
| Quality Clinical Research, Inc | Omaha | Nebraska | 68114 | — |
| Altea Research Institute | Las Vegas | Nevada | 89102 | — |
| Renown Institute for Neuroscience | Reno | Nevada | 89502 | — |
| Hassman Research Institute - NJ | Berlin | New Jersey | 08009 | — |
| Amici Clinical Research | Warren Township | New Jersey | 07059 | — |
| DENT Neurosciences Research Center | Amherst | New York | 14226 | — |
| Radiant Research, Inc. | Jamaica | New York | 11432 | — |
| Carolina Headache Institute | Durham | North Carolina | 27713 | — |
| Wake Research Associates LLC | Raleigh | North Carolina | 27612 | — |
| Ohio Clinical Research, LLC | Willoughby Hills | Ohio | 44094 | — |
| IPS Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Oregon Center for Clinical Investigations, Inc. | Salem | Oregon | 97301 | — |
| Lehigh Center For Clinical Research | Allentown | Pennsylvania | 18104 | — |
| Suburban Research Associates | Media | Pennsylvania | 19063 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Cns Healthcare | Memphis | Tennessee | 38119 | — |
| Nashville Neuroscience Group | Nashville | Tennessee | 37203 | — |
| Tekton Research | Austin | Texas | 78745 | — |
| DermResearch Inc | Austin | Texas | 78759 | — |
| DiscoveResearch, Inc. | Bryan | Texas | 77802 | — |
| Synexus US, L.P. Formally known as Texas Pharmaceutical Research, LP, DBA Research Across America | Dallas | Texas | 75234 | — |
| Central Texas Neurology Consultant | Round Rock | Texas | 78681 | — |
| Radiant Research, San Antonio Center for Clinical Research | San Antonio | Texas | 78229 | — |
| Road Runner Research LTD | San Antonio | Texas | 78258 | — |
| ClinPoint Trials, LLC | Waxahachie | Texas | 75165 | — |
| Advanced Clinical Research | West Jordan | Utah | 84088 | — |
| Tidewater Integrated Medical Research | Virginia Beach | Virginia | 23454 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Women's Clinical Research Center | Seattle | Washington | 98105 | — |
| Kingfisher Cooperative, LLC | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02848326, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 6, 2018 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02848326 live on ClinicalTrials.gov.