A Study of Atezolizumab as First-line Monotherapy for Advanced or Metastatic Non-Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT02848651. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Single-Arm Study of Atezolizumab Monotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer: Clinical Evaluation of Novel Blood-Based Diagnostics
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was a Phase II, open-label, prospective, multicenter study designed to evaluate the efficacy and safety of single-agent atezolizumab as a first-line therapy in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC). In addition, the primary biomarker objective was to measure blood tumor mutational burden (bTMB) and evaluate whether it can predict for improved clinical outcome with atezolizumab.
Study identification
- NCT ID
- NCT02848651
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 153 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 23, 2016 (Actual)
- Primary completion
- May 14, 2019 (Actual)
- Completion
- May 14, 2019 (Actual)
- Last update posted
- Apr 28, 2020
2016 – 2019
United States locations
- U.S. sites
- 20
- U.S. states
- 17
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Veterans Affairs Central California Health Care System | Fresno | California | 93703 | — |
| Memorial Regional Hospital | Hollywood | Florida | 33021 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| St. Alexius Medical Center | Hoffman Estates | Illinois | 60169 | — |
| Quincy Medical Group; Canc Ctr at Blessing Hosp | Quincy | Illinois | 62301 | — |
| Franciscan St. Francis Health; Research Services | Indianapolis | Indiana | 46237 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Michigan Cancer Rsch Cons | Ypsilanti | Michigan | 48197 | — |
| Virginia Piper Cancer Inst | Minneapolis | Minnesota | 55407 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Eastchester Center for Cancer Care | The Bronx | New York | 10469 | — |
| Levine Cancer Institute-Carolinas Medical Center; Levine Cancer Institute-Carolinas Medical Center | Charlotte | North Carolina | 28204 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Cancer Treatment Centers of America - Eastern Regional Medical Center | Philadelphia | Pennsylvania | 19124 | — |
| Avera Research Institute | Sioux Falls | South Dakota | 57105 | — |
| Univ of Texas SW Medical Ctr | Dallas | Texas | 75390 | — |
| Inova Health Care Services | Falls Church | Virginia | 22042 | — |
| Western WA Oncology Inc PS | Lacey | Washington | 98503 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02848651, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2020 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02848651 live on ClinicalTrials.gov.