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Completed Phase 1 Interventional

Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Patients With Neovascular AMD

ClinicalTrials.gov ID: NCT02859766

Public ClinicalTrials.gov record NCT02859766. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Safety and Systemic Pharmacokinetics After Single and Repeat Doses of Abicipar Pegol (AGN-150998) Intravitreal Injections in Patients With Neovascular Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety and characterize the systemic pharmacokinetics (PK) of free and vascular endothelial growth factor (VEGF)-bound abicipar following single and multiple intravitreal injections of abicipar pegol in treatment-naïve patients with neovascular age-related macular degeneration (AMD).

Study identification

NCT ID
NCT02859766
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Allergan
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 6, 2016
Primary completion
Oct 19, 2017
Completion
Oct 19, 2017
Last update posted
Feb 7, 2018

2016 – 2017

United States locations

U.S. sites
18
U.S. states
10
U.S. cities
18
Facility City State ZIP Site status
Retinal Consultants of Arizona Gilbert Arizona 85296
Win Retina Arcadia California 91006
Retina Vitreous Associates Medical Group Beverly Hills California 90211
Atlantis Retina Institute (Atlantis Eyecare) Huntington Beach California 92647
Jacobs Retina Center, Shiley Eye Institute, UCSD La Jolla California 92093
California Eye Specialists Medical Group, Inc-Private Clinic Pasadena California 91107
University of Miami Coral Gables Florida 33146
The Eye Institute of West Florida Largo Florida 33770
Retina Specialty Institute Pensacola Florida 32503
East Florida Eye Insititute Stuart Florida 34994
Center for Retina and Macular Disease Winter Haven Florida 33880
Raj K. Maturi, MD Indianapolis Indiana 46290
Massachusetts Eye & Ear Boston Massachusetts 02114
Eyesight Ophthalmic Services, PA Portsmouth New Hampshire 03801
Caroline Eye Associates Southern Pines North Carolina 28387
Cole Eye Institute, Cleveland Clinic Cleveland Ohio 44122
Rocky Mountain Retina Consultants Salt Lake City Utah 84107
Davis Duehr Dean Madison Wisconsin 53715

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02859766, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 7, 2018 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02859766 live on ClinicalTrials.gov.

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