ClinicalTrials.gov record
AMPLATZER™ Amulet™ LAA Occluder Trial
ClinicalTrials.gov ID: NCT02879448
Public ClinicalTrials.gov record NCT02879448. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
AMPLATZER™ Amulet™ Left Atrial Appendage Occluder Randomized Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN® left atrial appendage closure device in patients with non-valvular atrial fibrillation. Patients who are eligible for the trial will be randomized to receive either the Amulet device or the WATCHMAN device and will be followed for 5 years after device implant.
Study identification
- NCT ID
- NCT02879448
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,878 participants
Conditions and interventions
Conditions
Interventions
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2016
- Primary completion
- Dec 6, 2020
- Completion
- May 23, 2024
- Last update posted
- Feb 25, 2025
2016 – 2024
United States locations
- U.S. sites
- 85
- U.S. states
- 36
- U.S. cities
- 73
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research, LLC. | Huntsville | Alabama | 35801 | — |
| Banner-University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| Arizona Cardiovascular Research Center | Phoenix | Arizona | 85016 | — |
| St. Bernards Medical Center | Jonesboro | Arkansas | 72401 | — |
| Arkansas Heart Hospital | Little Rock | Arkansas | 72211 | — |
| Scripps Health | La Jolla | California | 92037 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| USC University Hospital | Los Angeles | California | 90033-5313 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| University of California - Davis Medical Center | Sacramento | California | 95817 | — |
| Mercy Medical Group - Cardiology | Sacramento | California | 95819 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| Pacific Heart Institute | Santa Monica | California | 90404 | — |
| South Denver Cardiology Associates PC | Littleton | Colorado | 80120 | — |
| Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Bradenton Cardiology Center | Bradenton | Florida | 34205 | — |
| Delray Medical Center | Delray Beach | Florida | 33484 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Baptist Medical Center | Jacksonville | Florida | 32207 | — |
| Watson Clinic Center | Lakeland | Florida | 33805 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176 | — |
| Tallahassee Research Institute | Tallahassee | Florida | 32308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Midwest Cardiovascular Institute | Naperville | Illinois | 60540 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Advocate Health and Hospitals Corporation | Oakbrook Terrace | Illinois | 60181 | — |
| St. Vincent Hospital | Indianapolis | Indiana | 46240-0970 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| Kansas City Cardiac Arrhythmia Research Foundation | Overland Park | Kansas | 66211 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Lahey Clinic Medical Center | Burlington | Massachusetts | 01805 | — |
| Charlton Memorial Hospital | Fall River | Massachusetts | 02720 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Sparrow Clinical Research Institute | Lansing | Michigan | 48912 | — |
| Beaumont Hospital, Royal Oak | Royal Oak | Michigan | 48073 | — |
| VA Medical Center Minneapolis | Minneapolis | Minnesota | 55417 | — |
| St. Cloud Hospital (Central MN Heart Clinic) | Saint Cloud | Minnesota | 56303 | — |
| St. Joseph's Hospital | Saint Paul | Minnesota | 55102 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| St. Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Nebraska Heart Institute | Lincoln | Nebraska | 68526 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601-1901 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Winthrop-University Hospital | Mineola | New York | 11501 | — |
| New York University Hospital | New York | New York | 10016 | — |
| Mount Sinai Hospital | New York | New York | 10019 | — |
| New York Presbyterian/Columbia University Medical Center | New York | New York | 10032 | — |
| Mission Health & Hospitals | Asheville | North Carolina | 28801 | — |
| Wake Forest University Medical Center Clinical Sciences | Winston-Salem | North Carolina | 27157-1045 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oklahoma Heart Institute at Utica | Tulsa | Oklahoma | 74104 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Lankenau Institute for Medical Research | Wynnewood | Pennsylvania | 19096 | — |
| WellSpan Health | York | Pennsylvania | 17403-3676 | — |
| Roper Hospital | Charleston | South Carolina | 29401 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| St. Thomas Hospital | Nashville | Tennessee | 37205 | — |
| Vanderbilt Heart Institute | Nashville | Tennessee | 37212 | — |
| Texas Cardiac Arrhythmia | Austin | Texas | 78705 | — |
| Austin Heart | Austin | Texas | 78756 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| The Heart Hospital Baylor Plano | Plano | Texas | 75093 | — |
| South Texas Cardiovascular Consultants | San Antonio | Texas | 78201 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| University of Vermont College of Medicine | Burlington | Vermont | 05405-0068 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Swedish Medical Center | Seattle | Washington | 98107 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
| Aurora Medical Group | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02879448, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 25, 2025 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02879448 live on ClinicalTrials.gov.