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Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Participants With Early Alzheimer's Disease

ClinicalTrials.gov ID: NCT02880956

Public ClinicalTrials.gov record NCT02880956. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Multiple Dose, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjects With Early Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study seeks to evaluate the efficacy and safety of ABBV-8E12 in participants with early Alzheimer's disease (AD).

Study identification

NCT ID
NCT02880956
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
453 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
55 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 26, 2017 (Actual)
Primary completion
Mar 30, 2021 (Actual)
Completion
Jul 28, 2021 (Actual)
Last update posted
Aug 26, 2022

2017 – 2021

United States locations

U.S. sites
38
U.S. states
21
U.S. cities
34
Facility City State ZIP Site status
Banner University of Arizona Medical Center Phoenix /ID# 151536 Phoenix Arizona 85006 —
Banner Sun Health Res Inst /ID# 151895 Sun City Arizona 85351 —
Irvine Clinical Research /ID# 162331 Irvine California 92614 —
Ucsd /Id# 152467 La Jolla California 92037 —
Ray Dolby Brain Health Center /ID# 154965 San Francisco California 94113 —
Univ California, San Francisco /ID# 152053 San Francisco California 94143-2204 —
Brain Matters Research /ID# 147796 Delray Beach Florida 33445 —
Neuropsychiatric Research Center of Southwest Florida /ID# 162332 Fort Myers Florida 33912 —
Mayo Clinic /ID# 151236 Jacksonville Florida 32224 —
Synexus Clinical Research US, Inc. /ID# 147804 Orlando Florida 32806-1044 —
University of South Florida /ID# 151890 Tampa Florida 33612 —
Synexus Clinical Research US, Inc /ID# 151633 The Villages Florida 32162-7116 —
Emory Midtown Infectious Disease Clinic /ID# 151492 Atlanta Georgia 30322 —
Atlanta Center for Medical Research /ID# 151550 Atlanta Georgia 30331 —
NeuroStudies.net, LLC /ID# 152746 Decatur Georgia 30030 —
Great Lakes Clinical Trials /ID# 152754 Chicago Illinois 60640 —
Advocate Lutheran General Hospital /ID# 152052 Park Ridge Illinois 60068 —
Southern IL Univ School of Med /ID# 151769 Springfield Illinois 62702 —
Indiana University /ID# 151861 Indianapolis Indiana 46202 —
University of Kansas Medical Center - Alzheimer's Disease Center /ID# 151554 Fairway Kansas 66205 —
University of Kentucky Chandler Medical Center /ID# 152753 Lexington Kentucky 40536 —
Johns Hopkins Bayview Med Cnt /ID# 151893 Baltimore Maryland 21224 —
Massachusetts General Hospital /ID# 151770 Boston Massachusetts 02114 —
Brigham and Women's Physicians /ID# 151882 Boston Massachusetts 02115 —
Hattiesburg Clinic /ID# 202388 Hattiesburg Mississippi 39401 —
Princeton Medical Institute /ID# 152934 Princeton New Jersey 08540 —
Scott Research Inc. /ID# 151880 Laurelton New York 11413 —
North Shore University Hospital /ID# 151632 New Hyde Park New York 11040 —
Duke Cancer Center /ID# 147828 Durham North Carolina 27710-3000 —
Oregon Health and Science University /ID# 151690 Portland Oregon 97239 —
Keystone Clinical Studies LLC /ID# 202305 Plymouth Meeting Pennsylvania 19462 —
Rhode Island Hospital /ID# 151538 Providence Rhode Island 02903 —
Vanderbilt University Medical Center /ID# 154547 Nashville Tennessee 37232-0011 —
Kerwin Research Center /ID# 147815 Dallas Texas 75231-4316 —
Houston Methodist Hospital /ID# 154810 Houston Texas 77030 —
McGovern Medical School /ID# 204860 Houston Texas 77054 —
University of Utah /ID# 151858 Salt Lake City Utah 84112-5500 —
Integrated Neurology Services /ID# 154863 Alexandria Virginia 22310 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02880956, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 26, 2022 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02880956 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →