Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Public ClinicalTrials.gov record NCT02889796. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo- and Active-controlled, Multicenter, Phase 3 Study to Assess the Efficacy and Safety of Filgotinib Administered for 52 Weeks in Combination With Methotrexate to Subjects With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate the effects of filgotinib versus placebo for the treatment of signs and symptoms of rheumatoid arthritis (RA) as measured by the percentage of participants achieving an American College of Rheumatology 20% improvement response (ACR20) at Week 12.
Study identification
- NCT ID
- NCT02889796
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,759 participants
Conditions and interventions
Conditions
Interventions
- Filgotinib Drug
- Placebo to match filgotinib Drug
- Adalimumab Drug
- Placebo to match adalimumab Drug
- MTX Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2016 (Actual)
- Primary completion
- Jul 4, 2018 (Actual)
- Completion
- Jun 20, 2019 (Actual)
- Last update posted
- Jun 9, 2021
2016 – 2019
United States locations
- U.S. sites
- 48
- U.S. states
- 18
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Covina | California | — | — |
| Not listed | Hemet | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | Palm Desert | California | — | — |
| Not listed | Upland | California | — | — |
| Not listed | Victorville | California | — | — |
| Not listed | Whittier | California | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | DeBary | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Miami Lakes | Florida | — | — |
| Not listed | New Port Richey | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Plantation | Florida | — | — |
| Not listed | Kansas City | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Elizabethtown | Kentucky | — | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | Cumberland | Maryland | — | — |
| Not listed | Hagerstown | Maryland | — | — |
| Not listed | Wheaton | Maryland | — | — |
| Not listed | Detroit | Michigan | — | — |
| Not listed | Saint Clair Shores | Michigan | — | — |
| Not listed | Eagan | Minnesota | — | — |
| Not listed | Hattiesburg | Mississippi | — | — |
| Not listed | Tupelo | Mississippi | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Toms River | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Bethlehem | Pennsylvania | — | — |
| Not listed | Duncansville | Pennsylvania | — | — |
| Not listed | Philadelphia | Pennsylvania | — | — |
| Not listed | Wyomissing | Pennsylvania | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Columbia | South Carolina | — | — |
| Not listed | Orangeburg | South Carolina | — | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | Beaumont | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Mesquite | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Webster | Texas | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 182 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02889796, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 9, 2021 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02889796 live on ClinicalTrials.gov.