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Terminated Phase 2 Interventional Results available

Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis

ClinicalTrials.gov ID: NCT02895100

Public ClinicalTrials.gov record NCT02895100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 4:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b Randomised, Double-blind, Placebo-controlled, Parallel, Adaptive 2-Stage, Multi-Centre Study to Evaluate the Safety and Efficacy of Oral PTG-100 Induction in Subjects With Moderate to Severe Active Ulcerative Colitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main objectives of this study are to evaluate the efficacy, safety, and tolerability of daily doses of PTG-100 in subjects with moderate to severe ulcerative colitis (UC).

Study identification

NCT ID
NCT02895100
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Protagonist Therapeutics, Inc.
Industry
Enrollment
98 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2016
Primary completion
Mar 25, 2018
Completion
Mar 25, 2018
Last update posted
Aug 20, 2025

2016 – 2018

United States locations

U.S. sites
21
U.S. states
12
U.S. cities
20
Facility City State ZIP Site status
Site Reference ID/Investigator # 101 Los Angeles California 90036
Site Reference ID/Investigator # 102 Los Angeles California 90036
Site Reference ID/Investigator # 125 Colorado Springs Colorado 80907
Site Reference ID/Investigator # 120 Miami Florida 33126
Site Reference ID/Investigator # 106 Port Orange Florida 32128
Site Reference ID/Investigator # 115 Saint Augustine Florida 32086
Site Reference ID/Investigator # 116 Sweetwater Florida 33172
Site Reference ID/Investigator # 100 Atlanta Georgia 30607
Site Reference ID/Investigator # 104 Marietta Georgia 30060
Site Reference ID/Investigator # 112 Suwanee Georgia 30024
Site Reference ID/Investigator # 107 Chicago Illinois 60611
Site Reference ID/Investigator # 126 Bastrop Louisiana 71220
Site Reference ID/Investigator # 114 Shreveport Louisiana 71105
Site Reference ID/Investigator # 117 Chevy Chase Maryland 20815
Site Reference ID/Investigator # 109 Great Neck New York 11021
Site Reference ID/Investigator # 122 New York New York 10065
Site Reference ID/Investigator # 119 Cincinnati Ohio 45219
Site Reference ID/Investigator # 110 Hermitage Tennessee 37076
Site Reference ID/Investigator # 128 Nashville Tennessee 37212
Site Reference ID/Investigator # 118 DeSoto Texas 75035
Site Reference ID/Investigator # 113 Richmond Virginia 23249

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02895100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2025 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02895100 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →