Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)
Public ClinicalTrials.gov record NCT02907177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Randomized, Double-blind, Parallel-group, add-on, Superiority Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical study compares the efficacy, safety, and tolerability of therapy with ponesimod vs placebo in subjects with active RMS who are treated with DMF (Tecfidera®).
Study identification
- NCT ID
- NCT02907177
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 136 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 30, 2017 (Actual)
- Primary completion
- Mar 26, 2020 (Actual)
- Completion
- Mar 26, 2020 (Actual)
- Last update posted
- May 18, 2021
2017 – 2020
United States locations
- U.S. sites
- 26
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Dpt of Neurology | Birmingham | Alabama | 35233 | — |
| Neuro-Pain Medical Center | Fresno | California | 93710 | — |
| SC3 Research - Pasadena | Pasadena | California | 91105 | — |
| Care Access Research - Santa Clarita | Santa Clarita | California | 91321 | — |
| Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Mountain View Clinical Research, Inc | Denver | Colorado | 80209 | — |
| Associated Neurologists | Danbury | Connecticut | 06810 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Neurology Associates - MS Center of Greater Orlando | Maitland | Florida | 32751 | — |
| Neurology Assoc of Ormond Beach - CNS Trials | Ormond Beach | Florida | 32174 | — |
| Suncoast Neuroscience Associates, Inc | St. Petersburg | Florida | 33713 | — |
| The MS Center of Vero Beach | Vero Beach | Florida | 32960 | — |
| Fort Wayne Neurological Center - North Office | Fort Wayne | Indiana | 46825 | — |
| University of Kansas Med Center | Kansas City | Kansas | 66160 | — |
| MidAmerica Neuroscience Research Foundation/Rowe Neurology | Lenexa | Kansas | 66214 | — |
| Henry Ford Health System - Neurology | Detroit | Michigan | 48202 | — |
| Univ of New Mexico - Health Sciences Center | Albuquerque | New Mexico | 87131 | — |
| NYU Langone Medical Center - MS Comprehensive Care Center | New York | New York | 10016 | — |
| Riverhills Healthcare, Inc. | Cincinnati | Ohio | 45212 | — |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | — |
| Neurology and Neuromuscular Center | Oklahoma City | Oklahoma | 73102 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital - Dpt Neurology MS Center | Philadelphia | Pennsylvania | 19107 | — |
| Advanced Neuroscience Institute | Franklin | Tennessee | 37064 | — |
| Neurology Center of San Antonio | San Antonio | Texas | 78258 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 93 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02907177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2021 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02907177 live on ClinicalTrials.gov.