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Terminated Phase 3 Interventional Results available

Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)

ClinicalTrials.gov ID: NCT02907177

Public ClinicalTrials.gov record NCT02907177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 5:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Multicenter, Randomized, Double-blind, Parallel-group, add-on, Superiority Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)

Study identification

NCT ID
NCT02907177
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Actelion
Industry
Enrollment
136 participants

Conditions and interventions

Interventions

  • Ponesimod Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 29, 2017
Primary completion
Mar 25, 2020
Completion
Mar 25, 2020
Last update posted
May 17, 2021

2017 – 2020

United States locations

U.S. sites
26
U.S. states
15
U.S. cities
25
Facility City State ZIP Site status
UAB Dpt of Neurology Birmingham Alabama 35233
Neuro-Pain Medical Center Fresno California 93710
SC3 Research - Pasadena Pasadena California 91105
Care Access Research - Santa Clarita Santa Clarita California 91321
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Torrance California 90502
University of Colorado Hospital Aurora Colorado 80045
Mountain View Clinical Research, Inc Denver Colorado 80209
Associated Neurologists Danbury Connecticut 06810
Bradenton Research Center Bradenton Florida 34205
Neurology Associates - MS Center of Greater Orlando Maitland Florida 32751
Neurology Assoc of Ormond Beach - CNS Trials Ormond Beach Florida 32174
Suncoast Neuroscience Associates, Inc St. Petersburg Florida 33713
The MS Center of Vero Beach Vero Beach Florida 32960
Fort Wayne Neurological Center - North Office Fort Wayne Indiana 46825
University of Kansas Med Center Kansas City Kansas 66160
MidAmerica Neuroscience Research Foundation/Rowe Neurology Lenexa Kansas 66214
Henry Ford Health System - Neurology Detroit Michigan 48202
Univ of New Mexico - Health Sciences Center Albuquerque New Mexico 87131
NYU Langone Medical Center - MS Comprehensive Care Center New York New York 10016
Riverhills Healthcare, Inc. Cincinnati Ohio 45212
OhioHealth Research Institute Columbus Ohio 43214
Neurology and Neuromuscular Center Oklahoma City Oklahoma 73102
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104
Thomas Jefferson University Hospital - Dpt Neurology MS Center Philadelphia Pennsylvania 19107
Advanced Neuroscience Institute Franklin Tennessee 37064
Neurology Center of San Antonio San Antonio Texas 78258

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 93 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02907177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 17, 2021 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02907177 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →