Study to Evaluate the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT02914522. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Combined Phase 2b/3, Double-Blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects With Moderately to Severely Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of this study are to evaluate the efficacy of filgotinib in the induction and maintenance treatment of moderately to severely active ulcerative colitis (UC) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or met protocol specified efficacy discontinuation criteria will have the option to enter a separate, long-term extension (LTE) study (Gilead Study GS-US-418-3899: NCT02914535).
Study identification
- NCT ID
- NCT02914522
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,351 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 14, 2016 (Actual)
- Primary completion
- Mar 31, 2020 (Actual)
- Completion
- Mar 31, 2020 (Actual)
- Last update posted
- Apr 21, 2021
2016 – 2020
United States locations
- U.S. sites
- 61
- U.S. states
- 26
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists of the Southeast | Dothan | Alabama | 36305 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| VA Long Beach Healthcare System | Long Beach | California | 90822 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| South Denver Gastroenterology, PC | Lone Tree | Colorado | 80124 | — |
| Connecticut GI PC-Research Division | Farmington | Connecticut | 06032 | — |
| UF Health at Shands Hospital | Gainesville | Florida | 32610 | — |
| Florida Research Institute | Lakewood Rch | Florida | 34211 | — |
| University of Miami Crohn's and Colitis Center | Miami | Florida | 33136 | — |
| Cordova Research Institute | Miami | Florida | 33155 | — |
| Gastroenterology Group of Naples | Naples | Florida | 34102 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Shafran Gastroenterology Center | Winter Park | Florida | 32789 | — |
| Florida Medical Clinic, P.A. | Zephyrhills | Florida | 33540 | — |
| Gastroenterology Associates of Central Georgia, LLC | Macon | Georgia | 31201 | — |
| Gastrointestinal Specialists of Georgia | Marietta | Georgia | 30060 | — |
| Atlanta Gastroenterology Specialist, PC | Suwanee | Georgia | 30024 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Louisville, Clinical Trials Unit | Louisville | Kentucky | 40202 | — |
| Delta Research Partners, LLC | Monroe | Louisiana | 71201 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Investigative Clinical Research | Annapolis | Maryland | 21401 | — |
| MGG Group Co., Inc., Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Gastro Center of Maryland | Columbia | Maryland | 21045 | — |
| Meritus Center for Clinical Research | Hagerstown | Maryland | 21742 | — |
| Massachusetts General Hospital - Crohn's and Colitis Center | Boston | Massachusetts | 02114 | — |
| Clinical Research Institute of Michigan, LLC | Chesterfield | Michigan | 48047 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| NY Scientific | Brooklyn | New York | 11235 | — |
| NYU Langone Long Island Clinical Research Associates | Great Neck | New York | 11021 | — |
| Carolina's GI Research, LLC | Raleigh | North Carolina | 27607 | — |
| Fargo Gastroenterology and Hepatology Clinic | Fargo | North Dakota | 58103 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| UC Health Physicians Clifton | Cincinnati | Ohio | 45219 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| Gastroenterology Associates of Orangeburg | Orangeburg | South Carolina | 29118 | — |
| Rapid City Medical Center | Rapid City | South Dakota | 57701 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Gastro One | Germantown | Tennessee | 38138 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| Vanderbilt University Medical Center - IBD Clinic | Nashville | Tennessee | 37212-1375 | — |
| San Antonio Military Medical Center | Fort Sam Houston | Texas | 78219 | — |
| DHAT Research Institute | Garland | Texas | 75044 | — |
| Baylor College of Medicine- Baylor Medical Center | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Clinical Associates in Research Therapeutics of America, LLC | San Antonio | Texas | 78212 | — |
| Gastroenterology Research of San Antonio | San Antonio | Texas | 78229 | — |
| Texas Digestive Disease Consultants | San Marcos | Texas | 78666 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092 | — |
| Spring Gastroenterology | The Woodlands | Texas | 77380 | — |
| HP Clinical Research | Bountiful | Utah | 84010 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Gastroenterology Associates Of Tidewater | Chesapeake | Virginia | 23320 | — |
| Emeritas Research Group LLC | Lansdowne Town Center | Virginia | 20176 | — |
| McGuire DVAMC | Richmond | Virginia | 23249 | — |
| University of Wisconsin Hospital & Clinics | Madison | Wisconsin | 53705 | — |
| Allegiance Research Specialists, LLC | Wauwatosa | Wisconsin | 53225 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 282 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02914522, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2021 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02914522 live on ClinicalTrials.gov.