A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma
Public ClinicalTrials.gov record NCT02918019. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIb, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Ranging Study to Assess the Efficacy and Safety of MSTT1041A in Patients With Uncontrolled Severe Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase IIb, randomized, placebo-controlled, double-blind, multicenter, multi-arm study which will evaluate efficacy, safety, and pharmacokinetic of MSTT1041A compared with placebo as add-on therapy in participants with severe, uncontrolled asthma who are receiving medium- or high-dose inhaled corticosteroid (ICS) therapy and at least one of the following additional controller medications: long-acting beta-agonists (LABA), leukotriene modifier (LTM), long-acting muscarinic antagonist (LAMA), or long-acting theophylline preparation. The total duration of this study for each participant is approximately 70 weeks including screening, run-in, treatment, and follow-up.
Study identification
- NCT ID
- NCT02918019
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 517 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 20, 2016 (Actual)
- Primary completion
- Apr 5, 2019 (Actual)
- Completion
- Jul 26, 2019 (Actual)
- Last update posted
- Dec 28, 2022
2016 – 2019
United States locations
- U.S. sites
- 43
- U.S. states
- 24
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Allergy & Asthma | Birmingham | Alabama | 35209 | — |
| Del Sol Research Management | Tucson | Arizona | 85710 | — |
| Kern Allergy Med Clinic, Inc. | Bakersfield | California | 93301 | — |
| Allergy & Asthma Care Center of Southern California | Long Beach | California | 90808 | — |
| CA Allergy & Asthma Med Grp; Medical Group, Inc. | Los Angeles | California | 90025 | — |
| Jonathan Corren MD, Inc. | Los Angeles | California | 90025 | — |
| Office of Robert N Wolfe MD | Los Angeles | California | 90048 | — |
| Advances in Medicine | Rancho Mirage | California | 92270 | — |
| Allergy & Asthma Consultants | Redwood City | California | 94063 | — |
| Bensch Research Associates | Stockton | California | 95207 | — |
| Allergy and Asthma Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| IMMUNOe Research Centers | Centennial | Colorado | 80112 | — |
| Asthma & Allergy; Associates, P.C. | Colorado Springs | Colorado | 80907 | — |
| Western States Clinical Research, Inc | Wheat Ridge | Colorado | 80033 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06519 | — |
| Emerald Coast Research Associates | Panama City | Florida | 32405 | — |
| Florida Premier Research Institute | Winter Park | Florida | 32789 | — |
| Atlanta Allergy & Asth Clin PC | Stockbridge | Georgia | 30281 | — |
| Asthma & Allergy of Idaho | Twin Falls | Idaho | 83301 | — |
| Asthma, Allergy & Sinus Center | Baltimore | Maryland | 21236 | — |
| Chesapeake Clinical Research Inc - CRN | Baltimore | Maryland | 21236 | — |
| Genesis Clinical Research & Consulting, LLC | Fall River | Massachusetts | 02720 | — |
| Infinity Medical Research Inc | North Dartmouth | Massachusetts | 02747 | — |
| Midwest Clinical Research LLC | St Louis | Missouri | 63141 | — |
| The Allergy and Asthma Center | Bellevue | Nebraska | 68123 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| American Health Research Inc. | Charlotte | North Carolina | 28277 | — |
| Allergy & Respiratory Center | Canton | Ohio | 44718 | — |
| Integrity People Services Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Vital Prospects Clin Res Pc | Tulsa | Oklahoma | 74136 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Asthma & Allergy Physicians of Rhode Island Clinical Research Institute (AAPRI CRI) | Warwick | Rhode Island | 02865 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Clinical Research Solutions PC | Knoxville | Tennessee | 37920 | — |
| Meharry Medical College; Clinical Trials Office | Nashville | Tennessee | 37208 | — |
| TTS Research | Boerne | Texas | 78006 | — |
| Elliot J. Ginchansky, MD, PA | Dallas | Texas | 75230 | — |
| Pioneer Research Solutions | Houston | Texas | 077099 | — |
| Metroplex Pulmonology & Sleep Center | McKinney | Texas | 75069 | — |
| Allergy & Asthma Research Center | San Antonio | Texas | 78229 | — |
| Allergy Associates of Utah | Murray | Utah | 84107 | — |
| Commonwealth Clinical Research Specialists | Richmond | Virginia | 23226 | — |
| Washington Univ School of Med | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 95 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02918019, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 28, 2022 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02918019 live on ClinicalTrials.gov.