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Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy

ClinicalTrials.gov ID: NCT02924883

Public ClinicalTrials.gov record NCT02924883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 12:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase II Study of the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Patients With HER2-Positive Locally Advanced or Metastatic Breast Cancer Who Have Received Prior Trastuzumab and Taxane Based Therapy

Study identification

NCT ID
NCT02924883
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
202 participants

Conditions and interventions

Interventions

  • Atezolizumab Drug
  • Placebo Other
  • Trastuzumab emtansine Drug

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 25, 2016
Primary completion
Dec 10, 2017
Completion
Feb 5, 2020
Last update posted
Feb 16, 2021

2016 – 2020

United States locations

U.S. sites
15
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Breastlink Med Group Inc Orange California 92868
University of Colorado Aurora Colorado 80045
MedStar Georgetown University Hospital (Lombardi Comprehensive Cancer Center) Washington D.C. District of Columbia 20007
SCRI Florida Cancer Specialists South Fort Myers Florida 33916
Florida Cancer Specialists; Saint Petersburg St. Petersburg Florida 33719
Northside Hospital Atlanta Georgia 30342
Johns Hopkins Univ Med Center Baltimore Maryland 21231
San Juan Oncology Associates Farmington New Mexico 87401
Laura and ISAAC Perlmutter Cancer Center at NYU Langone. New York New York 10016
Ohio State Uni Medical Center Columbus Ohio 43210
Magee Womens Hospital Pittsburgh Pennsylvania 15213
Cancer Care Associates of York York Pennsylvania 17403
SCRI Tennessee Oncology Chattanooga Chattanooga Tennessee 37404
Tennessee Oncology; Sarah Cannon Research Institute Nashville Tennessee 37203
University of Washington Seattle Washington 98195

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02924883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 16, 2021 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02924883 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →