Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease
Public ClinicalTrials.gov record NCT02927184. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess The Efficacy, Safety, and Tolerability of VK2809 Administered for 12 Weeks Followed by a 4-Week Off-Drug Phase in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will investigate the efficacy, safety, and tolerability of VK2809 in lowering LDL-C and liver fat content in patients with primary hypercholesterolemia and fatty liver disease. The primary efficacy endpoint is percent change from baseline LDL-C at the end of the treatment period (Week 12). Secondary endpoints include effects on liver fat content and other liver and lipid markers, as well as effects on safety and tolerability, and pharmacokinetic (PK) measurements.
Study identification
- NCT ID
- NCT02927184
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2016 (Actual)
- Primary completion
- Mar 26, 2019 (Actual)
- Completion
- Mar 26, 2019 (Actual)
- Last update posted
- Apr 26, 2021
2016 – 2019
United States locations
- U.S. sites
- 19
- U.S. states
- 10
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Radiant Research, Inc. | Chandler | Arizona | 85224 | — |
| SC Clinical Research | Garden Grove | California | 92844 | — |
| ACTCA | Los Angeles | California | — | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| North America Research, Inc | Pomona | California | 91767 | — |
| Orange County Research Center | Tustin | California | 92780 | — |
| Research Institute of South Florida | Miami | Florida | 33173 | — |
| Research Institute of South Florida | Miami | Florida | — | — |
| Avant Research Associates, LLC | Crowley | Louisiana | 70526 | — |
| HCI- MetroMedic Walk-in | New Bedford | Massachusetts | 02740 | — |
| HCI- MetroMedic Walk-in | New Bedford | Massachusetts | — | — |
| Flint Clinical Research, PLLC | Flint | Michigan | 48503 | — |
| Mid Hudson Medical | Hopewell Junction | New York | 12533 | — |
| CHEAR Center, LLC | The Bronx | New York | 10459 | — |
| Wake Research Associcates, LLC. | Raleigh | North Carolina | 27612 | — |
| Avant Research | Beaumont | Texas | 77702 | — |
| Clinical Trials of Texas, INC | San Antonio | Texas | 78229 | — |
| Radiant Research, Inc. | San Antonio | Texas | 78229 | — |
| Wasatch Clinical Research, LLC | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02927184, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2021 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02927184 live on ClinicalTrials.gov.