ClinicalTrials.gov record
Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
ClinicalTrials.gov ID: NCT02929329
Public ClinicalTrials.gov record NCT02929329. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects With Chronic Heart Failure With Reduced Ejection Fraction (GALACTIC-HF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if treatment with omecamtiv mecarbil when added to standard of care is well tolerated and superior to placebo in reducing the risk of cardiovascular death or heart failure events in adults with chronic heart failure with reduced ejection fraction (HFrEF).
Study identification
- NCT ID
- NCT02929329
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,256 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 6, 2017 (Actual)
- Primary completion
- Sep 14, 2020 (Actual)
- Completion
- Sep 14, 2020 (Actual)
- Last update posted
- Nov 5, 2021
2017 – 2020
United States locations
- U.S. sites
- 310
- U.S. states
- 45
- U.S. cities
- 252
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35233 | — |
| Research Site | Birmingham | Alabama | 35243 | — |
| Research Site | Birmingham | Alabama | 35294 | — |
| Research Site | Fort Payne | Alabama | 35967 | — |
| Research Site | Huntsville | Alabama | 35801 | — |
| Research Site | Mobile | Alabama | 36608 | — |
| Research Site | Scottsboro | Alabama | 35768 | — |
| Research Site | Tuscumbia | Alabama | 35674 | — |
| Research Site | Gilbert | Arizona | 85297 | — |
| Research Site | Phoenix | Arizona | 85032 | — |
| Research Site | Tucson | Arizona | 85710 | — |
| Research Site | Tucson | Arizona | 85724 | — |
| Research Site | Jonesboro | Arkansas | 72401 | — |
| Research Site | Little Rock | Arkansas | 72205 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Beverly Hills | California | 90211 | — |
| Research Site | Burbank | California | 91505 | — |
| Research Site | Carmichael | California | 95608 | — |
| Research Site | Fresno | California | 93701 | — |
| Research Site | Huntington Beach | California | 92648 | — |
| Research Site | Loma Linda | California | 92357 | — |
| Research Site | Long Beach | California | 90806 | — |
| Research Site | Long Beach | California | 90822 | — |
| Research Site | Los Alamitos | California | 90720 | — |
| Research Site | Los Angeles | California | 90033 | — |
| Research Site | Los Angeles | California | 90073 | — |
| Research Site | Mission Viejo | California | 92691 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Northridge | California | 91325 | — |
| Research Site | Redondo Beach | California | 90277 | — |
| Research Site | Riverside | California | 92506 | — |
| Research Site | Sacramento | California | 95819 | — |
| Research Site | San Francisco | California | 94115 | — |
| Research Site | San Pedro | California | 90732 | — |
| Research Site | Santa Ana | California | 92704 | — |
| Research Site | Santa Rosa | California | 95405 | — |
| Research Site | Stanford | California | 94305 | — |
| Research Site | Stockton | California | 95204 | — |
| Research Site | Torrance | California | 90502 | — |
| Research Site | Torrance | California | 90503 | — |
| Research Site | Tustin | California | 92780 | — |
| Research Site | Ventura | California | 93003 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | Colorado Springs | Colorado | 80909 | — |
| Research Site | Denver | Colorado | 80204 | — |
| Research Site | Denver | Colorado | 80218 | — |
| Research Site | Littleton | Colorado | 80120 | — |
| Research Site | Wheat Ridge | Colorado | 80033 | — |
| Research Site | Hartford | Connecticut | 06102 | — |
| Research Site | Stamford | Connecticut | 06905 | — |
| Research Site | Waterbury | Connecticut | 06708 | — |
| Research Site | West Haven | Connecticut | 06516 | — |
| Research Site | Newark | Delaware | 19718 | — |
| Research Site | Washington D.C. | District of Columbia | 20010 | — |
| Research Site | Washington D.C. | District of Columbia | 20037 | — |
| Research Site | Washington D.C. | District of Columbia | 20422 | — |
| Research Site | Altamonte Springs | Florida | 32714 | — |
| Research Site | Aventura | Florida | 33180 | — |
| Research Site | Bay Pines | Florida | 33744 | — |
| Research Site | Boynton Beach | Florida | 33472 | — |
| Research Site | Crystal River | Florida | 34429 | — |
| Research Site | Daytona Beach | Florida | 32117 | — |
| Research Site | Doral | Florida | 33126 | — |
| Research Site | Gainesville | Florida | 32608 | — |
| Research Site | Hialeah | Florida | 33012 | — |
| Research Site | Hialeah | Florida | 33013 | — |
| Research Site | Inverness | Florida | 34452 | — |
| Research Site | Jacksonville | Florida | 32209 | — |
| Research Site | Jacksonville | Florida | 32216 | — |
| Research Site | Miami | Florida | 33032 | — |
| Research Site | Miami | Florida | 33125 | — |
| Research Site | Miami | Florida | 33126 | — |
| Research Site | Miami | Florida | 33136 | — |
| Research Site | Miami | Florida | 33144 | — |
| Research Site | Miami | Florida | 33145 | — |
| Research Site | Miami | Florida | 33147 | — |
| Research Site | Miami | Florida | 33165 | — |
| Research Site | Miami | Florida | 33166 | — |
| Research Site | Miami | Florida | 33174 | — |
| Research Site | Miami Beach | Florida | 33140 | — |
| Research Site | Naples | Florida | 34102 | — |
| Research Site | Ocala | Florida | 34471 | — |
| Research Site | Palm Harbor | Florida | 34684 | — |
| Research Site | Pembroke Pines | Florida | 33028 | — |
| Research Site | Sarasota | Florida | 34232 | — |
| Research Site | Tampa | Florida | 33613 | — |
| Research Site | Zephyrhills | Florida | 33541 | — |
| Research Site | Athens | Georgia | 30606 | — |
| Research Site | Atlanta | Georgia | 30303 | — |
| Research Site | Atlanta | Georgia | 30309 | — |
| Research Site | Augusta | Georgia | 30909 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Smyrna | Georgia | 30082 | — |
| Research Site | Woodstock | Georgia | 30189 | — |
| Research Site | Honolulu | Hawaii | 96813 | — |
| Research Site | ‘Aiea | Hawaii | 96701 | — |
| Research Site | Arlington Heights | Illinois | 60005 | — |
| Research Site | Champaign | Illinois | 61820 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Fairview Heights | Illinois | 62208 | — |
| Research Site | Hazel Crest | Illinois | 60429 | — |
| Research Site | Maywood | Illinois | 60153 | — |
| Research Site | Oak Lawn | Illinois | 60453 | — |
| Research Site | Peoria | Illinois | 61606 | — |
| Research Site | Indianapolis | Indiana | 46227 | — |
| Research Site | Merrillville | Indiana | 46410 | — |
| Research Site | Muncie | Indiana | 47303 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | Richmond | Indiana | 47374 | — |
| Research Site | Valparaiso | Indiana | 46383 | — |
| Research Site | Des Moines | Iowa | 50314 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Kansas City | Kansas | 66160 | — |
| Research Site | Overland Park | Kansas | 66209 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Wichita | Kansas | 67226 | — |
| Research Site | Crestview Hills | Kentucky | 41017 | — |
| Research Site | Lexington | Kentucky | 40503 | — |
| Research Site | Louisville | Kentucky | 40202 | — |
| Research Site | Louisville | Kentucky | 40206 | — |
| Research Site | Louisville | Kentucky | 40216 | — |
| Research Site | Alexandria | Louisiana | 71301 | — |
| Research Site | Lake Charles | Louisiana | 70601 | — |
| Research Site | Monroe | Louisiana | 71201 | — |
| Research Site | New Orleans | Louisiana | 70112 | — |
| Research Site | Shreveport | Louisiana | 71103 | — |
| Research Site | Shreveport | Louisiana | 71105 | — |
| Research Site | West Monroe | Louisiana | 71291 | — |
| Research Site | Bangor | Maine | 04401 | — |
| Research Site | Biddeford | Maine | 04005 | — |
| Research Site | Portland | Maine | 04101 | — |
| Research Site | Scarborough | Maine | 04074 | — |
| Research Site | Baltimore | Maryland | 21201 | — |
| Research Site | Baltimore | Maryland | 21229 | — |
| Research Site | Baltimore | Maryland | 21236 | — |
| Research Site | Columbia | Maryland | 21044 | — |
| Research Site | Hagerstown | Maryland | 21740 | — |
| Research Site | Prince Frederick | Maryland | 20678 | — |
| Research Site | Salisbury | Maryland | 21804 | — |
| Research Site | Boston | Massachusetts | 02135 | — |
| Research Site | Haverhill | Massachusetts | 01830 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | Grand Blanc | Michigan | 48439 | — |
| Research Site | Kalamazoo | Michigan | 49008 | — |
| Research Site | Midland | Michigan | 48670 | — |
| Research Site | Royal Oak | Michigan | 48073 | — |
| Research Site | Saginaw | Michigan | 48601 | — |
| Research Site | Minneapolis | Minnesota | 55417 | — |
| Research Site | Saint Paul | Minnesota | 55101 | — |
| Research Site | Port Gibson | Mississippi | 39150 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Columbia | Missouri | 65201 | — |
| Research Site | Columbia | Missouri | 65212 | — |
| Research Site | Jefferson City | Missouri | 65109 | — |
| Research Site | Kansas City | Missouri | 64108 | — |
| Research Site | Kansas City | Missouri | 64128 | — |
| Research Site | Springfield | Missouri | 65807 | — |
| Research Site | St Louis | Missouri | 63110 | — |
| Research Site | Lincoln | Nebraska | 68506 | — |
| Research Site | Omaha | Nebraska | 68198 | — |
| Research Site | Las Vegas | Nevada | 89118 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | North Las Vegas | Nevada | 89086 | — |
| Research Site | Reno | Nevada | 89502 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Eatontown | New Jersey | 07724 | — |
| Research Site | Moorestown | New Jersey | 08057 | — |
| Research Site | Morristown | New Jersey | 07960 | — |
| Research Site | Newark | New Jersey | 07112 | — |
| Research Site | Ridgewood | New Jersey | 07450 | — |
| Research Site | Somerset | New Jersey | 08873 | — |
| Research Site | Voorhees Township | New Jersey | 08043 | — |
| Research Site | Albuquerque | New Mexico | 87106 | — |
| Research Site | Albany | New York | 12208 | — |
| Research Site | Brooklyn | New York | 11215 | — |
| Research Site | Buffalo | New York | 14215 | — |
| Research Site | Cortlandt Manor | New York | 10567 | — |
| Research Site | Johnson City | New York | 13790 | — |
| Research Site | Kingston | New York | 12401 | — |
| Research Site | Laurelton | New York | 11413 | — |
| Research Site | Mineola | New York | 11501 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | New York | New York | 10025 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Rochester | New York | 14621 | — |
| Research Site | Roslyn | New York | 11576 | — |
| Research Site | Saratoga Springs | New York | 12866 | — |
| Research Site | Stony Brook | New York | 11794 | — |
| Research Site | The Bronx | New York | 10467 | — |
| Research Site | Valhalla | New York | 10595 | — |
| Research Site | Asheville | North Carolina | 28803 | — |
| Research Site | Cary | North Carolina | 27518 | — |
| Research Site | Chapel Hill | North Carolina | 27599 | — |
| Research Site | Charlotte | North Carolina | 28203 | — |
| Research Site | Durham | North Carolina | 27705 | — |
| Research Site | Greensboro | North Carolina | 27401 | — |
| Research Site | Hickory | North Carolina | 28601 | — |
| Research Site | Lenoir | North Carolina | 28645 | — |
| Research Site | Lumberton | North Carolina | 28358 | — |
| Research Site | Mooresville | North Carolina | 28117 | — |
| Research Site | Pinehurst | North Carolina | 28374 | — |
| Research Site | Tabor City | North Carolina | 28463 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Cincinnati | Ohio | 45219 | — |
| Research Site | Cincinnati | Ohio | 45220 | — |
| Research Site | Cincinnati | Ohio | 45267 | — |
| Research Site | Cleveland | Ohio | 44106 | — |
| Research Site | Cleveland | Ohio | 44195 | — |
| Research Site | Columbus | Ohio | 43210 | — |
| Research Site | Columbus | Ohio | 43214 | — |
| Research Site | Dayton | Ohio | 45414 | — |
| Research Site | Dayton | Ohio | 45419 | — |
| Research Site | Kettering | Ohio | 45429 | — |
| Research Site | Marion | Ohio | 43302 | — |
| Research Site | Sandusky | Ohio | 44870 | — |
| Research Site | Wiloughby | Ohio | 44094 | — |
| Research Site | Oklahoma City | Oklahoma | 73135 | — |
| Research Site | Tulsa | Oklahoma | 74104 | — |
| Research Site | Tulsa | Oklahoma | 74127 | — |
| Research Site | Abington | Pennsylvania | 19001 | — |
| Research Site | Altoona | Pennsylvania | 16602 | — |
| Research Site | Butler | Pennsylvania | 16001 | — |
| Research Site | Camp Hill | Pennsylvania | 17011 | — |
| Research Site | Erie | Pennsylvania | 16502 | — |
| Research Site | Hershey | Pennsylvania | 17033 | — |
| Research Site | Jersey Shore | Pennsylvania | 17740 | — |
| Research Site | Lancaster | Pennsylvania | 17603 | — |
| Research Site | Philadelphia | Pennsylvania | 19102 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Philadelphia | Pennsylvania | 19114 | — |
| Research Site | Philadelphia | Pennsylvania | 19141 | — |
| Research Site | Pittsburgh | Pennsylvania | 15212 | — |
| Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Research Site | Sayre | Pennsylvania | 18840 | — |
| Research Site | Yardley | Pennsylvania | 19067 | — |
| Research Site | York | Pennsylvania | 17403 | — |
| Research Site | Pawtucket | Rhode Island | 02860 | — |
| Research Site | Providence | Rhode Island | 02906 | — |
| Research Site | Providence | Rhode Island | 02908 | — |
| Research Site | Warwick | Rhode Island | 02886 | — |
| Research Site | Charleston | South Carolina | 29401 | — |
| Research Site | Charleston | South Carolina | 29407 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Fort Mill | South Carolina | 29707 | — |
| Research Site | Greenville | South Carolina | 29605 | — |
| Research Site | Rock Hill | South Carolina | 29732 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Germantown | Tennessee | 38138 | — |
| Research Site | Jackson | Tennessee | 38301 | — |
| Research Site | Jackson | Tennessee | 38305 | — |
| Research Site | Knoxville | Tennessee | 37934 | — |
| Research Site | Memphis | Tennessee | 38104 | — |
| Research Site | Nashville | Tennessee | 37208 | — |
| Research Site | Nashville | Tennessee | 37212 | — |
| Research Site | Nashville | Tennessee | 37232 | — |
| Research Site | Oak Ridge | Tennessee | 37830 | — |
| Research Site | Powell | Tennessee | 37849 | — |
| Research Site | Tullahoma | Tennessee | 37388 | — |
| Research Site | Amarillo | Texas | 79106 | — |
| Research Site | Carrollton | Texas | 75006 | — |
| Research Site | Carrollton | Texas | 75010 | — |
| Research Site | Dallas | Texas | 75216 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Dallas | Texas | 75246 | — |
| Research Site | Denison | Texas | 75020 | — |
| Research Site | El Paso | Texas | 79935 | — |
| Research Site | Fort Sam Houston | Texas | 78234 | — |
| Research Site | Fort Worth | Texas | 76104 | — |
| Research Site | Galveston | Texas | 77555-0158 | — |
| Research Site | Gonzales | Texas | 78629 | — |
| Research Site | Houston | Texas | 77025 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Huntsville | Texas | 77340 | — |
| Research Site | Lubbock | Texas | 79430 | — |
| Research Site | McKinney | Texas | 75071 | — |
| Research Site | Odessa | Texas | 79761 | — |
| Research Site | Plano | Texas | 75024 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Tomball | Texas | 77375 | — |
| Research Site | Wichita Falls | Texas | 76301 | — |
| Research Site | Farmington | Utah | 84025 | — |
| Research Site | Murray | Utah | 84107 | — |
| Research Site | Salt Lake City | Utah | 84132 | — |
| Research Site | Burlington | Vermont | 05401 | — |
| Research Site | White River Junction | Vermont | 05009 | — |
| Research Site | Charlottesville | Virginia | 22908 | — |
| Research Site | Leesburg | Virginia | 20176 | — |
| Research Site | Lynchburg | Virginia | 24501 | — |
| Research Site | Manassas | Virginia | 20109 | — |
| Research Site | Norfolk | Virginia | 23510 | — |
| Research Site | Richmond | Virginia | 23226 | — |
| Research Site | Richmond | Virginia | 23249 | — |
| Research Site | Richmond | Virginia | 23298 | — |
| Research Site | Virginia Beach | Virginia | 23454 | — |
| Research Site | Puyallup | Washington | 98372 | — |
| Research Site | Seattle | Washington | 98122 | — |
| Research Site | Spokane | Washington | 99204 | — |
| Research Site | Huntington | West Virginia | 25702 | — |
| Research Site | Morgantown | West Virginia | 26506 | — |
| Research Site | Green Bay | Wisconsin | 54301 | — |
| Research Site | Madison | Wisconsin | 53705 | — |
| Research Site | Madison | Wisconsin | 53713 | — |
| Research Site | Madison | Wisconsin | 53792 | — |
| Research Site | Manitowoc | Wisconsin | 54220 | — |
| Research Site | Milwaukee | Wisconsin | 53201 | — |
| Research Site | Milwaukee | Wisconsin | 53226 | — |
| Research Site | Milwaukee | Wisconsin | 53295 | — |
| Research Site | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 723 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02929329, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2021 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02929329 live on ClinicalTrials.gov.