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Completed Phase 3 Interventional Results available

A Study for Patients Who Completed VITALITY-ALS (CY 4031)

ClinicalTrials.gov ID: NCT02936635

Public ClinicalTrials.gov record NCT02936635. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 10:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients With Amyotrophic Lateral Sclerosis (ALS) Who Completed VITALITY-ALS (CY 4031)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the long-term safety and tolerability of tirasemtiv in patients with ALS who had completed the double-blind placebo-controlled study of tirasemtiv in ALS (CY 4031).

Study identification

NCT ID
NCT02936635
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Cytokinetics
Industry
Enrollment
280 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 16, 2016
Primary completion
Oct 25, 2018
Completion
Oct 25, 2018
Last update posted
Jun 14, 2021

2016 – 2018

United States locations

U.S. sites
41
U.S. states
27
U.S. cities
39
Facility City State ZIP Site status
St. Joseph's Hospital and Medical Center - Barrow Neurology Clinics Phoenix Arizona 85013
Cedars-Sinai Medical Center Los Angeles California 90048
University of California, Irvine Orange California 92868
UC Davis Medical Center Sacramento California 95817
Forbes Norris MDA/ALS Research Center San Francisco California 94115
Stanford Hospital and Clinics Stanford California 94305
University of Colorado Hospital Anschutz Outpatient Pavilion Aurora Colorado 80045
Hospital for Special Care New Britain Connecticut 06053
George Washington University Medical Center Washington D.C. District of Columbia 20037
Mayo Clinic Jacksonville Florida 32224
University of Miami, Miller School of Medicine Miami Florida 33136
Carol & Frank Morsani Center for Advanced Health Care - University of South Florida Tampa Florida 33512
The Emory Clinic Atlanta Georgia 30322
Indiana University Indianapolis Indiana 46202
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
University of Kansas Medical Center Kansas City Kansas 66160
Johns Hopkins University Baltimore Maryland 21287
University of Massachusetts Memorial Medical Center/University of Massachusetts Medical School Worcester Massachusetts 01655
University of Michigan Health System Ann Arbor Michigan 48109
Henry Ford Health System Detroit Michigan 48202
Hennepin County Medical Center Minneapolis Minnesota 55415
St. Louis University, Department of Neurology & Psychiatry St Louis Missouri 63104
Barnes-Jewish Hospital St Louis Missouri 63110
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756
Hospital for Special Surgery New York New York 10021
Neurological Institute New York New York 10032
SUNY Upstate Medical University Syracuse New York 13210
Neurosciences Institute, Neurology - Charlotte Charlotte North Carolina 28207
Duke Neurological Disorders Clinic Durham North Carolina 27705
Department of Neurology, Wake Forest School of Medicine Winston-Salem North Carolina 27157
The Ohio State University Wexner Medical Center Columbus Ohio 43210
Providence Brain and Spine Inst. ALS Center Portland Oregon 97213
Penn State Milton S. Hershey Medical Center Hershey Pennsylvania 17033
Temple University School of Medicine Philadelphia Pennsylvania 19140
Vanderbilt University Medical Center - Clinical Research Center Nashville Tennessee 37232
Texas Neurology, PA Dallas Texas 75214
UTHSCSA - First Outpatient Research Unit San Antonio Texas 78229
University of Virginia Health System Charlottesville Virginia 22908
University of Washington Medical Center Seattle Washington 98195
West Virginia University Hospitals Morgantown West Virginia 26506
Froedtert Memorial Lutheran Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02936635, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 14, 2021 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02936635 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →