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Completed Phase 2 Interventional Results available

A Study to Evaluate the Effects of Basmisanil in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS) Treated With Antipsychotics

ClinicalTrials.gov ID: NCT02953639

Public ClinicalTrials.gov record NCT02953639. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 11:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IIb, Multicenter, Randomized, Double-Blind, Parallel Group, Placebo Controlled Study to Evaluate the Efficacy, Safety and Tolerability of Basmisanil (RO5186582) as Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia Treated With Antipsychotics

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This multicenter study assessed the effects of 24 weeks of basmisanil treatment on cognition and functioning of stable schizophrenia participants treated with antipsychotics.

Study identification

NCT ID
NCT02953639
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
214 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2016 (Actual)
Primary completion
Dec 12, 2019 (Actual)
Completion
Dec 12, 2019 (Actual)
Last update posted
Feb 9, 2021

2016 – 2019

United States locations

U.S. sites
37
U.S. states
16
U.S. cities
35
Facility City State ZIP Site status
Woodland International Research Group Inc. Little Rock Arkansas 72211 —
Woodland Research Northwest, LLC Rogers Arkansas 72758 —
ProScience Research Group Culver City California 90230 —
Collaborative Neuroscience Network, Inc. Garden Grove California 92845 —
California Clinical Trials Glendale California 91206 —
Alliance for Wellness, dba Alliance for Research Long Beach California 90807 —
Synergy Clinical Research National City California 91950 —
Pacific Research Partners, LLC Oakland California 94607 —
NRC Research Institute Orange California 92868 —
CNRI - Los Angeles, LLC Pico Rivera California 90660 —
Artemis Institute for Clinical Research, LLC San Diego California 92103 —
Collaborative Neuroscience Network Inc. Torrance California 90502 —
Yale School of Medicine - CT Mental Health Center (CMHC) - Schizophrenia Research Clinic New Haven Connecticut 06519 —
Vantage Clinical Trials Largo Florida 33770 —
Innovative Clinical Research, Inc. Lauderhill Florida 33319 —
Meridien Research Maitland Florida 32751 —
University of Miami Dept of Psychiatry Miami Florida 33136 —
Behavioral Clinical Research, Inc. North Miami Florida 33161 —
iResearch Atlanta Decatur Georgia 30030 —
Alexian Brothers Center for Psychiatric Research Hoffman Estates Illinois 60169 —
Community Clinical Research Center Anderson Indiana 46060 —
Booker, J. Gary, MD, APMC Shreveport Louisiana 71104-2136 —
Louisiana Clinical Research, LLC Shreveport Louisiana 71115 —
CBH Health Gaithersburg Maryland 20877 —
Boston Medical Center Boston Massachusetts 02114 —
Arch Clinical Trials, LLC St Louis Missouri 63118 —
St Louis Clinical Trials St Louis Missouri 63141 —
Hassman Research Institute Berlin New Jersey 08009 —
Neurobehavioral Research, Inc. Cedarhurst New York 11516 —
Manhattan Psychiatric Center; Psychopharmacology Research Unit New York New York 10035 —
Finger Lakes Clinical Research Rochester New York 14618 —
Neuro-Behavioral Clinical Research, Inc. Canton Ohio 44718 —
University Hospitals Cleveland Ohio 44106 —
Midwest Clinical Research Center Dayton Ohio 45417 —
Pillar Clinical Research LLC Garland Texas 75042 —
University Hills Clinical Research - Irving;Office of Dr. Knesevich Irving Texas 75062 —
Northwest Clinical Research Center Bellevue Washington 98007 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02953639, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 9, 2021 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02953639 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →