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Completed Phase 2 Interventional Results available

A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)

ClinicalTrials.gov ID: NCT02953678

Public ClinicalTrials.gov record NCT02953678. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to assess the efficacy of ruxolitinib in combination with corticosteroids in subjects with Grades II to IV steroid-refractory acute graft-versus-host disease (GVHD).

Study identification

NCT ID
NCT02953678
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Incyte Corporation
Industry
Enrollment
71 participants

Conditions and interventions

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 30, 2016 (Actual)
Primary completion
Jan 31, 2018 (Actual)
Completion
Aug 14, 2019 (Actual)
Last update posted
Nov 24, 2021

2016 – 2019

United States locations

U.S. sites
38
U.S. states
22
U.S. cities
32
Facility City State ZIP Site status
Not listed Tucson Arizona 85719 —
Not listed Duarte California 31010 —
Not listed La Jolla California 92903 —
Not listed Los Angeles California 90033 —
Not listed Los Angeles California 90095 —
Not listed Stanford California 94306 —
Not listed Denver Colorado 80218 —
Not listed Gainesville Florida 32610 —
Not listed Miami Florida 33136 —
Not listed Tampa Florida 33612 —
Not listed Atlanta Georgia 30322 —
Not listed Chicago Illinois 60611 —
Not listed Chicago Illinois 60637 —
Not listed Lexington Kentucky 40536-0293 —
Not listed Boston Massachusetts 02114 —
Not listed Grand Rapids Michigan 49503 —
Not listed Minneapolis Minnesota 55455 —
Not listed St Louis Missouri 63110 —
Not listed Hackensack New Jersey 07601 —
Not listed New York New York 10022 —
Not listed New York New York 10065 —
Not listed Rochester New York 14642 —
Not listed Charlotte North Carolina 28204 —
Not listed Cincinnati Ohio 45242 —
Not listed Cleveland Ohio 44195 —
Not listed Philadelphia Pennsylvania 19104 —
Not listed Philadelphia Pennsylvania 19107 —
Not listed Pittsburgh Pennsylvania 15224 —
Not listed Pittsburgh Pennsylvania 15232 —
Not listed Nashville Tennessee 37203 —
Not listed Nashville Tennessee 37232 —
Not listed Dallas Texas 75246 —
Not listed San Antonio Texas 78229 —
Not listed Salt Lake City Utah 84112 —
Not listed Seattle Washington 98109 —
Not listed Morgantown West Virginia 26506 —
Not listed Madison Wisconsin 53705 —
Not listed Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02953678, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 24, 2021 · Synced Oct 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02953678 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →