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Terminated Phase 1 Interventional Results available

A Study Of PF-06747143, As Single Agent Or In Combination With Standard Chemotherapy In Adult Patients With Acute Myeloid Leukemia

ClinicalTrials.gov ID: NCT02954653

Public ClinicalTrials.gov record NCT02954653. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 10, 2026, 5:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1 DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVENOUS PF-06747143, ADMINISTERED AS SINGLE AGENT OR IN COMBINATION WITH STANDARD CHEMOTHERAPY IN ADULT PATIENTS WITH ACUTE MYELOID LEUKEMIA

Study identification

NCT ID
NCT02954653
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
8 participants

Conditions and interventions

Interventions

  • Azacitidine Drug
  • Cytarabine Drug
  • Daunorubicin Drug
  • Decitabine Drug
  • PF-06747143 Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 27, 2016
Primary completion
Dec 4, 2017
Completion
Dec 4, 2017
Last update posted
Nov 20, 2019

2016 – 2017

United States locations

U.S. sites
4
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
The University of Arizona Cancer Center-North Campus Tucson Arizona 85719
Banner-University Medical Center Tucson Tucson Arizona 85724
The University of Chicago Medical Center Chicago Illinois 60637
Wake Forest Baptist Health Winston-Salem North Carolina 27157

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02954653, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 20, 2019 · Synced May 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02954653 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →