Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo
Public ClinicalTrials.gov record NCT02957682. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Praluent on Neurocognitive Function in Patients With Heterozygous Familial Hypercholesterolemia or With Non-Familial Hypercholesterolemia at High and Very High Cardiovascular Risk
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate the effect on mental state (known as "neurocognitive function") with use of Praluent.
Study identification
- NCT ID
- NCT02957682
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 2,176 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2, 2016 (Actual)
- Primary completion
- Mar 5, 2020 (Actual)
- Completion
- Mar 5, 2020 (Actual)
- Last update posted
- May 7, 2021
2016 – 2020
United States locations
- U.S. sites
- 73
- U.S. states
- 26
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Regeneron Study Site | Auburn | Alabama | 36830 | — |
| Regeneron Study Site | Birmingham | Alabama | 35209 | — |
| Regeneron Study Site | Mobile | Alabama | 36608 | — |
| Regeneron Study Site | Beverly Hills | California | 90210 | — |
| Regeneron Study Site | Los Gatos | California | 95032 | — |
| Regeneron Study Site | North Hollywood | California | 91606 | — |
| Regeneron Study Site | Port Hueneme | California | 93041 | — |
| Regeneron Study Site | Westminster | California | 92683 | — |
| Regeneron Study Site 1 | Aurora | Colorado | 80012 | — |
| Regeneron Study Site 2 | Aurora | Colorado | 80012 | — |
| Regeneron Study Site | Colorado Springs | Colorado | 80906 | — |
| Regeneron Study Site | Lake Worth | Florida | 33461 | — |
| Regeneron Study Site | Lake Worth | Florida | 33462 | — |
| Regeneron Study Site | Miami Springs | Florida | 33166 | — |
| Regeneron Study Site | Covington | Georgia | 30014 | — |
| Regeneron Study Site | Champaign | Illinois | 61822 | — |
| Regeneron Study Site | Chicago | Illinois | 60602 | — |
| Regeneron Study Site | Chicago | Illinois | 60640 | — |
| Regeneron Study Site | Rock Island | Illinois | 61201 | — |
| Regeneron Study Site | Evansville | Indiana | 47714 | — |
| Regeneron Study Site | Indianapolis | Indiana | 46237 | — |
| Regeneron Study Site | Ames | Iowa | 50010-3014 | — |
| Regeneron Study Site | Iowa City | Iowa | 52242 | — |
| Regeneron Study Site | Waterloo | Iowa | 50702 | — |
| Regeneron Study Site | Hutchinson | Kansas | 67502 | — |
| Regeneron Study Site | Newton | Kansas | 67114 | — |
| Regeneron Study Site | Overland Park | Kansas | 66209 | — |
| Regeneron Study Site | Louisville | Kentucky | 40213 | — |
| Regeneron Study Site | Bangor | Maine | 04401 | — |
| Regeneron Study Site | Baltimore | Maryland | 21229 | — |
| Regeneron Study Site | Oxon Hill | Maryland | 20745 | — |
| Regeneron Study Site | Minneapolis | Minnesota | 55407 | — |
| Regeneron Study Site | Olive Branch | Mississippi | 38654 | — |
| Regeneron Study Site | Washington | Missouri | 63090 | — |
| Regeneron Study Site | Buffalo | New York | 14215 | — |
| Regeneron Study Site | New Hyde Park | New York | 11042 | — |
| Regeneron Study Site | Cary | North Carolina | 27518 | — |
| Regeneron Study Site | Charlotte | North Carolina | 28209 | — |
| Regeneron Study Site | Charlotte | North Carolina | 28277 | — |
| Regeneron Study Site | Greensboro | North Carolina | 27401 | — |
| Regeneron Study Site | Hickory | North Carolina | 28601 | — |
| Regeneron Study Site | High Point | North Carolina | 27262 | — |
| Regeneron Study Site | Raleigh | North Carolina | 27609 | — |
| Regeneron Study Site | Rocky Mount | North Carolina | 27804 | — |
| Regeneron Study Site | Salisbury | North Carolina | 28144 | — |
| Regeneron Study Site | Statesville | North Carolina | 28625 | — |
| Regeneron Study Site | Wilmington | North Carolina | 28401 | — |
| Regeneron Study Site | Winston-Salem | North Carolina | 27103 | — |
| Regeneron Study Site | Cincinnati | Ohio | 45219 | — |
| Regeneron Study Site | Cleveland | Ohio | 44122 | — |
| Regeneron Study Site | Dayton | Ohio | 45414 | — |
| Regeneron Study Site | Duncansville | Pennsylvania | 16635 | — |
| Regeneron Study Site | Charleston | South Carolina | 29407 | — |
| Regeneron Study Site | Greenville | South Carolina | 29485 | — |
| Regeneron Study Site | Summerville | South Carolina | 29615 | — |
| Regeneron Study Site | Rapid City | South Dakota | 57701 | — |
| Regeneron Study Site | Bristol | Tennessee | 37620 | — |
| Regeneron Study Site | Knoxville | Tennessee | 37760 | — |
| Regeneron Study Site | Knoxville | Tennessee | 37912 | — |
| Regeneron Study Site | Knoxville | Tennessee | 37938 | — |
| Regeneron Study Site | Powell | Tennessee | 37849 | — |
| Regeneron Study Site | Dallas | Texas | 75231 | — |
| Regeneron Study Site | Houston | Texas | 77002 | — |
| Regeneron Study Site | Houston | Texas | 77027 | — |
| Regeneron Study Site | Schertz | Texas | 78154 | — |
| Regeneron Study Site | Shavano Park | Texas | 78231 | — |
| Regeneron Study Site | Falls Church | Virginia | 22601 | — |
| Regeneron Study Site | Winchester | Virginia | 22042 | — |
| Regeneron Study Site | Burien | Washington | 98166 | — |
| Regeneron Study Site | Everett | Washington | 98405 | — |
| Regeneron Study Site | Tacoma | Washington | 98405 | — |
| Regeneron Study Site | Walla Walla | Washington | 99362 | — |
| Regeneron Study Site | Manitowoc | Wisconsin | 54220 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 115 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02957682, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2021 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02957682 live on ClinicalTrials.gov.