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Completed Phase 2 Interventional Results available

Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia (ADVANCE)

ClinicalTrials.gov ID: NCT02970305

Public ClinicalTrials.gov record NCT02970305. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 12:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To evaluate the efficacy and safety of adjunctive pimavanserin compared with adjunctive placebo in the treatment of the negative symptoms of schizophrenia

Study identification

NCT ID
NCT02970305
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Enrollment
403 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 4, 2016 (Actual)
Primary completion
Oct 16, 2019 (Actual)
Completion
Oct 28, 2019 (Actual)
Last update posted
Dec 22, 2020

2016 – 2019

United States locations

U.S. sites
33
U.S. states
17
U.S. cities
30
Facility City State ZIP Site status
Not listed Phoenix Arizona 85012 —
Not listed Rogers Arkansas 72758 —
Not listed Bellflower California 90706 —
Not listed Lemon Grove California 91945 —
Not listed Norwalk California 90650 —
Not listed San Diego California 92103 —
Not listed San Diego California 92123 —
Not listed Santa Ana California 92705 —
Not listed Torrance California 90502 —
Not listed Hialeah Florida 33016 —
Not listed Lauderhill Florida 33319 —
Not listed Miami Florida 33122 —
Not listed Miami Florida 33136 —
Not listed Tampa Florida 33613 —
Not listed Atlanta Georgia 30328 —
Not listed Atlanta Georgia 30331 —
Not listed Decatur Georgia 30030 —
Not listed Marietta Georgia 30060 —
Not listed Chicago Illinois 60611 —
Not listed Hoffman Estates Illinois 60169 —
Not listed Wichita Kansas 67214 —
Not listed Ann Arbor Michigan 48105 —
Not listed Las Vegas Nevada 89102 —
Not listed Berlin New Jersey 08009 —
Not listed Albuquerque New Mexico 87109 —
Not listed Rochester New York 14618 —
Not listed Charlotte North Carolina 28211 —
Not listed Durham North Carolina 27704 —
Not listed Oklahoma City Oklahoma 73116 —
Not listed Downingtown Pennsylvania 19335 —
Not listed Charleston South Carolina 29407 —
Not listed Irving Texas 75062 —
Not listed Richardson Texas 75080 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02970305, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 22, 2020 · Synced Oct 18, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02970305 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →