Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
Public ClinicalTrials.gov record NCT02970669. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Randomized, Double-blind, Double Dummy, Parallel Group, Active-controlled 8-week Study and 8-week Open Label Extension to Evaluate the Effect of Initiation of Sacubitril/Valsartan on Objective Measures of Waking Activity and Sleep, as Health-related Quality of Life Functions in Subjects With Heart Failure and Reduced Ejection Fraction (AWAKE-HF).
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection fraction.
Study identification
- NCT ID
- NCT02970669
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 140 participants
Conditions and interventions
Conditions
Interventions
- sacubitril/valsartan (LCZ696) Drug
- enalapril Drug
- matching placebo sacubitril/valsartan (LCZ696) Drug
- matching placebo enalapril Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 16, 2016 (Actual)
- Primary completion
- Mar 19, 2018 (Actual)
- Completion
- Mar 19, 2018 (Actual)
- Last update posted
- Oct 7, 2021
2016 – 2018
United States locations
- U.S. sites
- 23
- U.S. states
- 9
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Fort Payne | Alabama | 35967 | — |
| Novartis Investigative Site | Beverly Hills | California | 90211 | — |
| Novartis Investigative Site | Stockton | California | 95204 | — |
| Novartis Investigative Site | West Hills | California | 91307 | — |
| Novartis Investigative Site | Doral | Florida | 33126 | — |
| Novartis Investigative Site | Inverness | Florida | 34452 | — |
| Novartis Investigative Site | Ormond Beach | Florida | 32174 | — |
| Novartis Investigative Site | Port Orange | Florida | 32127 | — |
| Novartis Investigative Site | Lutherville | Maryland | 21093 | — |
| Novartis Investigative Site | East Brunswick | New Jersey | 08816 | — |
| Novartis Investigative Site | Ridgewood | New Jersey | 07450 | — |
| Novartis Investigative Site | Columbia | South Carolina | 29203 | — |
| Novartis Investigative Site | Greenville | South Carolina | 29615 | — |
| Novartis Investigative Site | Lancaster | South Carolina | 29720 | — |
| Novartis Investigative Site | Allen | Texas | 75002-3688 | — |
| Novartis Investigative Site | McKinney | Texas | 75013 | — |
| Novartis Investigative Site | New Braunfels | Texas | 78130 | — |
| Novartis Investigative Site | San Antonio | Texas | 78229 | — |
| Novartis Investigative Site | San Marcos | Texas | 78666 | — |
| Novartis Investigative Site | Sherman | Texas | 75092 | — |
| Novartis Investigative Site | Tomball | Texas | 77375 | — |
| Novartis Investigative Site | Midlothian | Virginia | 23114 | — |
| Novartis Investigative Site | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02970669, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2021 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02970669 live on ClinicalTrials.gov.