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Completed Phase 3 Interventional Results available

Safety of Intravenous Neridronic Acid in CRPS

ClinicalTrials.gov ID: NCT02972359

Public ClinicalTrials.gov record NCT02972359. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label Safety Trial of Intravenous Neridronic Acid in Subjects With Complex Regional Pain Syndrome (CRPS)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The aim of this trial was to investigate the safety of intravenous neridronic acid in patients with complex regional pain syndrome (CRPS). The trial was divided into 3 periods: a 60-day enrollment period, a treatment period consisting of 4 infusions over 10 days, and a follow-up period of approximately 50 weeks (with visits at Week 2, Week 6, Week 12, Week 26, Week 39, and Week 52).

Study identification

NCT ID
NCT02972359
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Grünenthal GmbH
Industry
Enrollment
580 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 20, 2016 (Actual)
Primary completion
Jan 9, 2019 (Actual)
Completion
Jan 9, 2019 (Actual)
Last update posted
Nov 21, 2019

2016 – 2019

United States locations

U.S. sites
42
U.S. states
21
U.S. cities
38
Facility City State ZIP Site status
US017: Cactus Clinical Research, Inc. Phoenix Arizona 85012 —
US028: Quality of Life Medical and Research Centers LLC Tucson Arizona 85712 —
US045: Woodland International Research Group Little Rock Arkansas 72211 —
US044: Woodland Research Northwest Rogers Arkansas 72758 —
US012: Orange County Research Institute Anaheim California 92801 —
US022: Core Healthcare Group Cerritos California 90703 —
US033: Alliance Research Centers Laguna Hills California 92653 —
US027: The Helm Center for Pain Management Laguna Woods California 92637 —
US003: Samaritan Center for Medical Research Los Gatos California 95032 —
US010: Catalina Research Institute, LLC Montclair California 91763 —
US014: Northern California Research Sacramento California 95821 —
US034: Mountain View Clinical Research, Inc. Denver Colorado 80209 —
US032: South Lake Pain Institute Clermont Florida 34711 —
US001: Sunrise Research Institute, Inc Miami Florida 33130 —
US046: AMPM Research Clinic Miami Florida 33169 —
US035: Compass Research Orlando Florida 32806 —
US031: Gold Coast Research, LLC Plantation Florida 33317 —
US011: Clinical Research of West Florida, Inc. Tampa Florida 33603 —
US040: Palm Beach Research Center West Palm Beach Florida 33409 —
US026: Better Health Clinical Research Inc. Newnan Georgia 30265 —
US004: Northwestern University - Feinberg School of Medicine - Rehabilitation Institute of Chicago (RIC) Chicago Illinois 60611 —
US036: University Anesthesiologists, S.C. Chicago Illinois 60612 —
US029: Great Lakes Clinical Trials LLC Chicago Illinois 60640 —
US005: International Clinical Research Institute Overland Park Kansas 66210 —
US037: St. Louis Clinical Trials, LC St Louis Missouri 63141 —
US051: Creighton University, Osteoporosis Research Center Omaha Nebraska 68122 —
US002: Princeton Medical Institute Princeton New Jersey 08540 —
US049: Premier Pain Centers, LLC Shrewsbury New Jersey 07702 —
US048: Albany Medical College Albany New York 12208 —
US043: Translational Pain Research, University of Rochester Rochester New York 14618 —
US009: The Center for Clinical Research, LLC Winston-Salem North Carolina 27103 —
US016: North Star Medical Research, LLC Middleburg Heights Ohio 44130 —
US007: Medical Research International Oklahoma City Oklahoma 73109-4520 —
US006: Abington Neurological Associates, LTD. Willow Grove Pennsylvania 19090 —
US020: Clinical Trials of South Carolina Charleston South Carolina 29406 —
US038: Vanderbilt University Medical Center Nashville Tennessee 37212-1050 —
US019: Austin Center for Clinical Research Austin Texas 78758 —
US008: Pioneer Research Solutions Houston Texas 77099 —
US023: Axios Research, LLC Salt Lake City Utah 84106 —
US018: Washington Center for Pain Management Bellevue Washington 98004 —
US015: Northwest Clinical Research Center Bellevue Washington 98007 —
US013: Swedish Pain Services/ Research Institute Seattle Washington 98122 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02972359, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 21, 2019 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02972359 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →