A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
Public ClinicalTrials.gov record NCT02975934. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TRITON3: A Multicenter, Randomized, Open Label Phase 3 Study of Rucaparib Versus Physician's Choice of Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Associated With Homologous Recombination Deficiency
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine how participants with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib versus treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.
Study identification
- NCT ID
- NCT02975934
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 405 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2017 (Actual)
- Primary completion
- Aug 25, 2022 (Actual)
- Completion
- Aug 8, 2024 (Actual)
- Last update posted
- Jul 25, 2025
2017 – 2024
United States locations
- U.S. sites
- 61
- U.S. states
- 25
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| Arizona Oncology Associates - USOR | Tucson | Arizona | 85704 | — |
| University of Southern California | Beverly Hills | California | 90210 | — |
| Alliance Research Centers | Laguna Hills | California | 92653 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| San Bernardino Urological Associates | San Bernardino | California | 92404 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Pacific Hematology Oncology Associates | San Francisco | California | 94115 | — |
| San Francisco VA Health Care System | San Francisco | California | 94121 | — |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | — |
| St. Joseph Heritage Healthcare | Santa Rosa | California | 95403 | — |
| Kaiser Permanente, Northern CA | Vallejo | California | 94589 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Medical Oncology Hematology Consultants - USOR | Newark | Delaware | 19713 | — |
| Boca Raton Community Hospital, Inc. | Boca Raton | Florida | 33486 | — |
| University of Florida Health Cancer Center | Orlando | Florida | 32806 | — |
| Atlanta Urological Group | Atlanta | Georgia | 30312 | — |
| Kaiser Permanente Medical Group | Honolulu | Hawaii | 96819 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Maryland Oncology Hematology P.A. | Columbia | Maryland | 21044 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| VA Ann Arbor Healthcare System | Ann Arbor | Michigan | 48105 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Minnesota Oncology Hematology, P.A. | Minneapolis | Minnesota | 55404 | — |
| Minnesota Veterans Research Institute | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic - Rochester, MN | Rochester | Minnesota | 55902 | — |
| Alegent Health Bergan Mercy Hospital , GU Research Network | Omaha | Nebraska | 68130 | — |
| Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| Premier Urology Associates | Lawrenceville | New Jersey | 08648 | — |
| Roswell Park | Buffalo | New York | 14263 | — |
| NYU Perlmutter Cancer Center | New York | New York | 10016 | — |
| Memorial Sloan Kettering CC | New York | New York | 10065 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| Premier Medical Group of the Hudson Valley PC | Poughkeepsie | New York | 12601 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| University of North Carolina Lineberger Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Carolina Urology Partners | Concord | North Carolina | 28025 | — |
| Durham VA Medical Center | Durham | North Carolina | 27705 | — |
| Oncology Hematology Care | Cincinnati | Ohio | 45211 | — |
| The Urology Group | Cincinnati | Ohio | 45212 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Clinical Research Solutions | Middleburg Heights | Ohio | 44130 | — |
| VA Portland Health Care System | Portland | Oregon | 97219 | — |
| Northwest Cancer Specialist DBA Compass Oncology | Portland | Oregon | 97227 | — |
| Knight Cancer Institute | Portland | Oregon | 97239 | — |
| Urology Associates Clinical Research | Nashville | Tennessee | 37209 | — |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| UT Health Science Center | Houston | Texas | 77030 | — |
| Texas Oncology Cancer Center-Round Rock | Round Rock | Texas | 78681 | — |
| Urology of Virginia | Virginia Beach | Virginia | 23462 | — |
| MultiCare Regional Cancer Center - Gig Harbor | Gig Harbor | Washington | 98335 | — |
| VA Puget Sound HCS | Seattle | Washington | 98108 | — |
| University of Washington Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 89 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02975934, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 25, 2025 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02975934 live on ClinicalTrials.gov.