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Not listed Phase 1 Interventional

Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer

ClinicalTrials.gov ID: NCT02977468

Public ClinicalTrials.gov record NCT02977468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer With and Without Intra-operative RT: a Window of Opportunity Study

Study identification

NCT ID
NCT02977468
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eileen Connolly
Other
Enrollment
15 participants

Conditions and interventions

Interventions

  • Merck 3475 Pembrolizumab Drug
  • Intraoperative radiation therapy (IORT) Radiation

Drug · Radiation

Eligibility (public fields only)

Age range
21 Years to 80 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 24, 2017
Primary completion
Dec 30, 2024
Completion
Dec 30, 2025
Last update posted
Jun 19, 2024

2017 – 2025

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
Emory University Atlanta Georgia 30322 Recruiting
Loyola University Chicago Maywood Illinois 60153 Recruiting
Columbia University Irving Medical Center New York New York 10032 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02977468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 19, 2024 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02977468 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →