Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Public ClinicalTrials.gov record NCT02980874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SAPPHIRE: A Randomized, Masked, Controlled Trial To Study The Safety And Efficacy Of Suprachoroidal CLS-TA In Conjunction With Intravitreal Aflibercept In Subjects With Retinal Vein Occlusion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, multicenter, randomized, masked, controlled, parallel group study of 12 months duration in treatment naïve subjects with RVO.
Study identification
- NCT ID
- NCT02980874
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 460 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2017 (Actual)
- Primary completion
- Dec 10, 2018 (Actual)
- Completion
- Dec 10, 2018 (Actual)
- Last update posted
- Apr 14, 2021
2017 – 2018
United States locations
- U.S. sites
- 58
- U.S. states
- 23
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants, Ltd. | Peoria | Arizona | 85381 | — |
| Retinal Consultants of Arizona and Retinal Research Institute | Phoenix | Arizona | 85014-2709 | — |
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85021 | — |
| Associated Retina Consultants, Ltd. | Phoenix | Arizona | 85381 | — |
| Retina Centers P.C. | Tucson | Arizona | 85704 | — |
| California Retina Research Consultants | Bakersfield | California | 93309 | — |
| Retina Vitreous Medical Group Clinical Research | Beverly Hills | California | 90211-1841 | — |
| Atlantis Eyecare | Huntington Beach | California | 92647 | — |
| Jacobs Retina Center at the Shiley Eye Institute, UCSD | La Jolla | California | 92093 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| East Bay Retina Consultants Inc. | Oakland | California | 95409 | — |
| Southern California Desert Retina Consultants | Palm Desert | California | 92211 | — |
| Retina Institute of California | Palm Desert | California | 92260 | — |
| Retina Consultants San Diego | Poway | California | 92064-2526 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| California Retina Consultants CRC | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94599 | — |
| Colorado Retina Associates | Golden | Colorado | 80401 | — |
| New England Retina Associates | Hamden | Connecticut | 06518 | — |
| MedEye Associates | Miami | Florida | 33143-5188 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Sarasota Retina Institute | Sarasota | Florida | 34239 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Emory Eye Center | Atlanta | Georgia | 30322 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| Marietta Eye Clinic | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| Illinois Eye and Ear Infirmary, UIC | Chicago | Illinois | 60612 | — |
| Illinois Retina Associates | Chicago | Illinois | 60657 | — |
| Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Retina Associates, PA | Shawnee Mission | Kansas | 66204 | — |
| Retina and Vitrous Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| Wilmer Eye Institute John Hopkins University | Baltimore | Maryland | 21287-0005 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740-5940 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Retina Associates of NJ | Teaneck | New Jersey | 07666 | — |
| Western Carolina Retinal Associates, PA | Asheville | North Carolina | 28803 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic Foundation/Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| Oregon Retina Institute | Medford | Oregon | 97504 | — |
| Casey Eye Institute/Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701-7374 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606-1224 | — |
| Texas Retina Associates-Arlington | Arlington | Texas | 76012-2505 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Retina Consultants of Houston | Houston | Texas | 77030 | — |
| Valley Retina Institute | McAllen | Texas | 78503 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240-1502 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| University of Utah HSC - John A. Moran Eye Center | Salt Lake City | Utah | 84132 | — |
| Retina Institute of Virginia | Richmond | Virginia | 23235 | — |
| Virginia Retina Center | Warrenton | Virginia | 20186 | — |
| University of Wisconsin-Madison | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02980874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 14, 2021 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02980874 live on ClinicalTrials.gov.