ClinicalTrials.gov record
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia
ClinicalTrials.gov ID: NCT02981628
Public ClinicalTrials.gov record NCT02981628. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 9, 2026, 1:11 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518) in Children and Young Adults With Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
Study identification
- NCT ID
- NCT02981628
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Children's Oncology Group
- Network
- Enrollment
- 80 participants
Conditions and interventions
Conditions
Interventions
- Asparaginase Erwinia chrysanthemi Drug
- Biospecimen Collection Procedure
- Bone Marrow Aspiration and Biopsy Procedure
- Calaspargase Pegol Drug
- Cyclophosphamide Drug
- Cytarabine Drug
- Diagnostic Imaging Testing Procedure
- Inotuzumab Ozogamicin Biological
- Leucovorin Calcium Drug
- Lumbar Puncture Procedure
- Methotrexate Drug
- Pegaspargase Drug
- Vincristine Drug
Drug · Procedure · Biological
Eligibility (public fields only)
- Age range
- 1 Year to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 18, 2017
- Primary completion
- Dec 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- May 3, 2026
2017 – 2026
United States locations
- U.S. sites
- 156
- U.S. states
- 47
- U.S. cities
- 130
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital of Alabama | Birmingham | Alabama | 35233 | Recruiting |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | Recruiting |
| Banner Children's at Desert | Mesa | Arizona | 85202 | Recruiting |
| Phoenix Childrens Hospital | Phoenix | Arizona | 85016 | Recruiting |
| Banner University Medical Center - Tucson | Tucson | Arizona | 85719 | Active, not recruiting |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202-3591 | Recruiting |
| Kaiser Permanente Downey Medical Center | Downey | California | 90242 | Recruiting |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | Active, not recruiting |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | Suspended |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | Recruiting |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Valley Children's Hospital | Madera | California | 93636 | Active, not recruiting |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | Recruiting |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | Recruiting |
| Children's Hospital of Orange County | Orange | California | 92868 | Recruiting |
| Lucile Packard Children's Hospital Stanford University | Palo Alto | California | 94304 | Recruiting |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | Recruiting |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | Recruiting |
| Rady Children's Hospital - San Diego | San Diego | California | 92123 | Recruiting |
| UCSF Medical Center-Mission Bay | San Francisco | California | 94158 | Recruiting |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | Active, not recruiting |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | Recruiting |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Denver | Colorado | 80218 | Recruiting |
| Connecticut Children's Medical Center | Hartford | Connecticut | 06106 | Recruiting |
| Yale University | New Haven | Connecticut | 06520 | Active, not recruiting |
| Alfred I duPont Hospital for Children | Wilmington | Delaware | 19803 | Recruiting |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Golisano Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | Recruiting |
| UF Health Cancer Institute - Gainesville | Gainesville | Florida | 32610 | Active, not recruiting |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida | 33021 | Recruiting |
| Nemours Children's Clinic-Jacksonville | Jacksonville | Florida | 32207 | Recruiting |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | Recruiting |
| AdventHealth Orlando | Orlando | Florida | 32803 | Recruiting |
| Nemours Children's Hospital | Orlando | Florida | 32827 | Recruiting |
| Nemours Children's Clinic - Pensacola | Pensacola | Florida | 32504 | Recruiting |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | Active, not recruiting |
| Tampa General Hospital | Tampa | Florida | 33606 | Recruiting |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Tampa | Florida | 33607 | Suspended |
| Saint Mary's Medical Center | West Palm Beach | Florida | 33407 | Recruiting |
| Children's Healthcare of Atlanta - Arthur M Blank Hospital | Atlanta | Georgia | 30329 | Recruiting |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | Recruiting |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | Recruiting |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | Recruiting |
| Lurie Children's Hospital-Chicago | Chicago | Illinois | 60611 | Recruiting |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | Recruiting |
| Loyola University Medical Center | Maywood | Illinois | 60153 | Recruiting |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | Recruiting |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | Recruiting |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | Recruiting |
| Ascension Saint Vincent Indianapolis Hospital | Indianapolis | Indiana | 46260 | Active, not recruiting |
| Blank Children's Hospital | Des Moines | Iowa | 50309 | Recruiting |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | Recruiting |
| University of Kentucky/Markey Cancer Center | Lexington | Kentucky | 40536 | Recruiting |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | Recruiting |
| Children's Hospital New Orleans | New Orleans | Louisiana | 70118 | Recruiting |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | Recruiting |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | Recruiting |
| Maine Children's Cancer Program | Scarborough | Maine | 04074 | Recruiting |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | Recruiting |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | Recruiting |
| National Institutes of Health Clinical Center | Bethesda | Maryland | 20892 | Active, not recruiting |
| Tufts Children's Hospital | Boston | Massachusetts | 02111 | Active, not recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| UMass Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | Recruiting |
| C S Mott Children's Hospital | Ann Arbor | Michigan | 48109 | Recruiting |
| Michigan State University | East Lansing | Michigan | 48823 | Active, not recruiting |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | Recruiting |
| Corewell Health Children's | Royal Oak | Michigan | 48073 | Recruiting |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Minneapolis | Minnesota | 55404 | Recruiting |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | Recruiting |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | Recruiting |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | Recruiting |
| University of Missouri Children's Hospital | Columbia | Missouri | 65212 | Recruiting |
| Children's Mercy Hospitals and Clinics | Kansas City | Missouri | 64108 | Recruiting |
| Cardinal Glennon Children's Medical Center | St Louis | Missouri | 63104 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | Recruiting |
| Children's Hospital and Medical Center of Omaha | Omaha | Nebraska | 68114 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Sunrise Hospital and Medical Center | Las Vegas | Nevada | 89109 | Recruiting |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | 89135 | Recruiting |
| Summerlin Hospital Medical Center | Las Vegas | Nevada | 89144 | Recruiting |
| Renown Regional Medical Center | Reno | Nevada | 89502 | Recruiting |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | Recruiting |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Recruiting |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | Recruiting |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08903 | Recruiting |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | Recruiting |
| Saint Joseph's Regional Medical Center | Paterson | New Jersey | 07503 | Recruiting |
| Albany Medical Center | Albany | New York | 12208 | Recruiting |
| Maimonides Medical Center | Brooklyn | New York | 11219 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| NYU Langone Hospital - Long Island | Mineola | New York | 11501 | Recruiting |
| The Steven and Alexandra Cohen Children's Medical Center of New York | New Hyde Park | New York | 11040 | Recruiting |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | Recruiting |
| Mount Sinai Hospital | New York | New York | 10029 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| University of Rochester | Rochester | New York | 14642 | Active, not recruiting |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | Recruiting |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | Recruiting |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | Recruiting |
| New York Medical College | Valhalla | New York | 10595 | Active, not recruiting |
| Mission Hospital | Asheville | North Carolina | 28801 | Recruiting |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | Active, not recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Suspended |
| East Carolina University | Greenville | North Carolina | 27834 | Suspended |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | Recruiting |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | Recruiting |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308 | Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | Recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | Active, not recruiting |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Recruiting |
| Dayton Children's Hospital | Dayton | Ohio | 45404 | Recruiting |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo | Ohio | 43606 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Legacy Emanuel Children's Hospital | Portland | Oregon | 97227 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Recruiting |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | Recruiting |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | Recruiting |
| Penn State Children's Hospital | Hershey | Pennsylvania | 17033 | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Saint Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | Recruiting |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | Recruiting |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| Prisma Health Richland Hospital | Columbia | South Carolina | 29203 | Recruiting |
| BI-LO Charities Children's Cancer Center | Greenville | South Carolina | 29605 | Recruiting |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | Recruiting |
| T C Thompson Children's Hospital | Chattanooga | Tennessee | 37403 | Recruiting |
| East Tennessee Childrens Hospital | Knoxville | Tennessee | 37916 | Recruiting |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105 | Recruiting |
| The Children's Hospital at TriStar Centennial | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | Recruiting |
| Dell Children's Medical Center of Central Texas | Austin | Texas | 78723 | Recruiting |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | Recruiting |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | Recruiting |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | Recruiting |
| El Paso Children's Hospital | El Paso | Texas | 79905 | Recruiting |
| Cook Children's Medical Center | Fort Worth | Texas | 76104 | Recruiting |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | Recruiting |
| Covenant Children's Hospital | Lubbock | Texas | 79410 | Recruiting |
| UMC Cancer Center / UMC Health System | Lubbock | Texas | 79415 | Recruiting |
| Children's Hospital of San Antonio | San Antonio | Texas | 78207 | Recruiting |
| Methodist Children's Hospital of South Texas | San Antonio | Texas | 78229 | Recruiting |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | Suspended |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | Recruiting |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | Recruiting |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | Recruiting |
| Children's Hospital of The King's Daughters | Norfolk | Virginia | 23507 | Recruiting |
| Seattle Children's Hospital | Seattle | Washington | 98105 | Recruiting |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99204 | Recruiting |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | Recruiting |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | Active, not recruiting |
| Children's Hospital of Wisconsin | Milwaukee | Wisconsin | 53226 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02981628, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02981628 live on ClinicalTrials.gov.