A Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Subjects With Progressive Supranuclear Palsy (PSP)
Public ClinicalTrials.gov record NCT02985879. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to assess efficacy, safety, tolerability, and pharmacokinetics of ABBV-8E12 in participants with progressive supranuclear palsy (PSP).
Study identification
- NCT ID
- NCT02985879
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 378 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 12, 2016 (Actual)
- Primary completion
- Nov 20, 2019 (Actual)
- Completion
- Nov 20, 2019 (Actual)
- Last update posted
- Feb 3, 2021
2016 – 2019
United States locations
- U.S. sites
- 27
- U.S. states
- 18
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham - Main /ID# 144892 | Birmingham | Alabama | 35233 | — |
| Mayo Clinic - Scottsdale /ID# 144893 | Scottsdale | Arizona | 85259 | — |
| Cedars-Sinai Medical Center /ID# 149775 | Beverly Hills | California | 90211 | — |
| Ucsd /Id# 144905 | La Jolla | California | 92093 | — |
| Usc /Id# 149773 | Los Angeles | California | 90033 | — |
| University of California, Los Angeles /ID# 144896 | Los Angeles | California | 90095 | — |
| Univ California, San Francisco /ID# 144897 | San Francisco | California | 94143-2204 | — |
| Rocky Mountain Movement Disorders Center /ID# 153397 | Englewood | Colorado | 80113-2736 | — |
| University of Florida - Archer /ID# 144906 | Gainesville | Florida | 32610 | — |
| Mayo Clinic /ID# 144911 | Jacksonville | Florida | 32224 | — |
| University of South Florida /ID# 144912 | Tampa | Florida | 33612 | — |
| Georgia Regents University /ID# 144908 | Augusta | Georgia | 30912 | — |
| Rush University Medical Center /ID# 144894 | Chicago | Illinois | 60612 | — |
| University of Chicago /ID# 148672 | Chicago | Illinois | 60637-1443 | — |
| Indiana University /ID# 149036 | Indianapolis | Indiana | 46202 | — |
| University of Kentucky Chandler Medical Center /ID# 144891 | Lexington | Kentucky | 40536 | — |
| Mayo Clinic - Rochester /ID# 144895 | Rochester | Minnesota | 55905-0001 | — |
| St. Luke's Hosp. of Kansas Cit /ID# 168629 | Kansas City | Missouri | 64111 | — |
| Cleveland Clinic Lou Ruvo Cent /ID# 148919 | Las Vegas | Nevada | 89106 | — |
| Rutgers Robert Wood Johnson /ID# 144901 | New Brunswick | New Jersey | 08901 | — |
| COLUMBIA University Medical Center /ID# 149037 | New York | New York | 10032-3725 | — |
| Cleveland Clinic Main Campus /ID# 144885 | Cleveland | Ohio | 44195 | — |
| Oregon Health and Science University /ID# 149774 | Portland | Oregon | 97239 | — |
| Vanderbilt Univ Med Ctr /ID# 144898 | Nashville | Tennessee | 37232-0011 | — |
| Kerwin Research Center /ID# 144904 | Dallas | Texas | 75231-4316 | — |
| McGovern Medical School /ID# 149236 | Houston | Texas | 77054 | — |
| Central Texas Neurology Consul /ID# 167417 | Round Rock | Texas | 78681 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02985879, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2021 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02985879 live on ClinicalTrials.gov.