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Completed Phase 2 Interventional Results available

A Dose-ranging Study of Orvepitant in Patients With Chronic Refractory Cough

ClinicalTrials.gov ID: NCT02993822

Public ClinicalTrials.gov record NCT02993822. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Randomized, Placebo Controlled Study of the Efficacy and Safety of Three Doses of Orvepitant in Subjects With Chronic Refractory Cough

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the effectiveness of three doses of orvepitant, taken once a day, in the treatment of chronic refractory cough.

Study identification

NCT ID
NCT02993822
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Nerre Therapeutics Ltd.
Industry
Enrollment
315 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 22, 2017 (Actual)
Primary completion
Jan 14, 2019 (Actual)
Completion
Jan 24, 2019 (Actual)
Last update posted
Apr 26, 2022

2017 – 2019

United States locations

U.S. sites
46
U.S. states
22
U.S. cities
41
Facility City State ZIP Site status
Study Site 15 Chandler Arizona 85224 —
Study Site 43 Los Angeles California 90025 —
Study Site 52 Mission Viejo California 92692 —
Study Site 20 San Diego California 92108 —
Study Site 28 San Jose California 95117 —
Study Site 25 Centennial Colorado 80112 —
Study Site 36 Colorado Springs Colorado 80907 —
Study Site 48 Waterbury Connecticut 06708 —
Study Site 68 Clearwater Florida 33765 —
Study Site 59 Jacksonville Florida 32224 —
Study Site 12 Largo Florida 33778 —
Study Site 62 Miami Florida 33060 —
Study Site 57 Miami Florida 33186 —
Study Site 33 Tampa Florida 33613 —
Study Site 11 Winter Park Florida 32789 —
Study Site 60 Meridian Idaho 83642 —
Study Site 39 Normal Illinois 61761 —
Study Site 34 Baltimore Maryland 21236 —
Study Site 42 Edina Minnesota 55435 —
Study Site 41 Minneapolis Minnesota 55402 —
Study Site 37 Rochester Minnesota 55905 —
Study Site 27 Missoula Montana 59808 —
Study Site 16 Las Vegas Nevada 89128 —
Study Site 32 Rochester New York 14618 —
Study Site 55 Charlotte North Carolina 28204 —
Study Site 24 Charlotte North Carolina 28207 —
Study Site 53 Charlotte North Carolina 29732 —
Study Site 50 Gastonia North Carolina 28054 —
Study Site 54 Greensboro North Carolina 27403 —
Study Site 73 Mooresville North Carolina 28117 —
Study Site 71 Raleigh North Carolina 27612 —
Study Site 56 Cincinnati Ohio 45231 —
Study Site 74 Oklahoma City Oklahoma 73131 —
Study Site 26 Tulsa Oklahoma 74136 —
Study Site 38 East Providence Rhode Island 02914 —
Study Site 21 Charleston South Carolina 29420 —
Study Site 72 Charleston South Carolina 29464 —
Study Site 22 Dallas Texas 75231 —
Study Site 35 Dallas Texas 75231 —
Study Site 10 Houston Texas 77074 —
Study Site 49 San Antonio Texas 78229 —
Study Site 23 Waco Texas 76712 —
Study Site 58 Salt Lake City Utah 84108 —
Study Site 19 Charlottesville Virginia 22911 —
Study Site 14 Bellingham Washington 98225 —
Study Site 13 Greenfield Wisconsin 53228 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02993822, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 26, 2022 · Synced Oct 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02993822 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →