ClinicalTrials.gov record
Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder
ClinicalTrials.gov ID: NCT03002077
Public ClinicalTrials.gov record NCT03002077. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the long-term safety and tolerability of rapastinel as an adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD).
Study identification
- NCT ID
- NCT03002077
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 617 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 3, 2017 (Actual)
- Primary completion
- Dec 6, 2018 (Actual)
- Completion
- Dec 6, 2018 (Actual)
- Last update posted
- Jun 22, 2020
2017 – 2018
United States locations
- U.S. sites
- 128
- U.S. states
- 32
- U.S. cities
- 107
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Harmonex, Inc. | Dothan | Alabama | 36303 | — |
| NoesisPharma | Phoenix | Arizona | 85032 | — |
| Woodland International Research Group | Little Rock | Arkansas | 72211 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| California Pharmaceutical Research Institute, Inc | Anaheim | California | 92804 | — |
| Southern California Research LLC. | Beverly Hills | California | 90036 | — |
| ATP Clinical Research Inc. | Costa Mesa | California | 92626 | — |
| ProScience Research Group | Culver City | California | 90230 | — |
| Collaborative Neuroscience Network, LLC | Garden Grove | California | 92845 | — |
| Behavioral Research Specialists, LLC | Glendale | California | 91206 | — |
| Sun Valley Research Center | Imperial | California | 92251 | — |
| Irvine Center for Clinical Research, Inc | Irvine | California | 92614 | — |
| Synergy Clinical Research Center of Escondido | Lemon Grove | California | 91945 | — |
| Synergy San Diego | Lemon Grove | California | 91945 | — |
| Pharmacology Research Institute | Los Alamitos | California | 90720 | — |
| Pacific Research Partners; LLC. | Oakland | California | 94607 | — |
| Excell Research | Oceanside | California | 92056 | — |
| NRC Research Institute | Orange | California | 92868 | — |
| Asclepes Research Centers | Panorama City | California | 91402 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| CITrials | Riverside | California | 92506 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| PCSD Feighner Research | San Diego | California | 92108 | — |
| Artemis Institute for Clinical Research | San Marcos | California | 92078 | — |
| Thomas M. Shiovitz, M.D., Inc., DBA California Neuroscience Research Medical Group, Inc., | Sherman Oaks | California | 91403 | — |
| Viking Clinical Research | Temecula | California | 92591 | — |
| Pacific Clinical Research Medical | Upland | California | 91786 | — |
| MCB Clinical Research Center | Colorado Springs | Colorado | 80910 | — |
| Comprehensive Psychiatric Care | Norwich | Connecticut | 06360 | — |
| Meridien Research | Bradenton | Florida | 34201 | — |
| Gulfcoast Clinical Research Center | Fort Myers | Florida | 33912 | — |
| Sarkis Clinical Trials | Gainesville | Florida | 32607 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Reliable Clinical Research | Hialeah | Florida | 33012 | — |
| Clinical Neuroscience Solutions, Inc | Jacksonville | Florida | 32256 | — |
| Meridien Research | Lakeland | Florida | 33805 | — |
| Innovative Clinical Research, Inc | Lauderhill | Florida | 33319 | — |
| Innova Clinical Trials Inc. | Miami | Florida | 33145 | — |
| International Research Associates, LLC | Miami | Florida | 33183 | — |
| Research Centers of America | Oakland Park | Florida | 33334 | — |
| Medical Research Group of Central Florida | Orange City | Florida | 32763 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | — |
| Combined Research Orlando Phase I-IV | Orlando | Florida | 32807 | — |
| Millenia Psychiatry & Research, Inc | Orlando | Florida | 32839 | — |
| Olympian Clinical Research | Tampa | Florida | 33609 | — |
| University of South Florida, Psychiatry and Behavioral Neurosciences | Tampa | Florida | 33613 | — |
| Institute for Advanced Medical Research | Atlanta | Georgia | 30005 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta, LLC | Decatur | Georgia | 30030 | — |
| Northwest Behavioral Research Center | Marietta | Georgia | 30060 | — |
| Iris Research | Smyrna | Georgia | 30080 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Alexian Brothers Center for Psychiatric Research | Hoffman Estates | Illinois | 60169 | — |
| Capstone Clinical Research | Libertyville | Illinois | 60048 | — |
| AMR - Baber Research, Inc. | Naperville | Illinois | 60563 | — |
| Psychiatric Associates | Overland Park | Kansas | 66211 | — |
| Heartland Research Associates | Wichita | Kansas | 67207 | — |
| Lake Charles Clinical Trials | Lake Charles | Louisiana | 70629 | — |
| Louisiana Clinical Research | Shreveport | Louisiana | 71101 | — |
| J Gary Booker, MD APMC | Shreveport | Louisiana | 71104 | — |
| Sheppard Pratt Health System | Baltimore | Maryland | 21204 | — |
| Pharmasite Research, Inc | Baltimore | Maryland | 21208 | — |
| CBH Health | Gaithersburg | Maryland | 20850 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| ActivMed Practices & Research, Inc. | Methuen | Massachusetts | 01844 | — |
| Coastal Research Associates | South Weymouth | Massachusetts | 02190 | — |
| Adams Clinical Trials | Watertown | Massachusetts | 02472 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| Psychiatric Care and Research Center | O'Fallon | Missouri | 63368 | — |
| St. Charles Psychiatric Associates - Midwest Research Group | Saint Charles | Missouri | 63304 | — |
| Millennium Psychiatric Associates | St Louis | Missouri | 63141 | — |
| Premier Psychiatric Research Institute, LLC | Lincoln | Nebraska | 68526 | — |
| Altea Research | Las Vegas | Nevada | 89102 | — |
| Healthy Perspectives - Innovative Mental Health Services. PLLC | Nashua | New Hampshire | 03060 | — |
| Hassman Research Institute, LLC | Berlin | New Jersey | 08009 | — |
| Center for Emotional Fitness | Cherry Hill | New Jersey | 08002 | — |
| Pharmaceutical Research Associates Inc | Marlton | New Jersey | 08053 | — |
| Global Medical Institute, LLC | Princeton | New Jersey | 08540 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Albuquerque Neuroscience, Inc | Albuquerque | New Mexico | 87109 | — |
| SPRI Clinical Trials, Inc | Brooklyn | New York | 11235 | — |
| Bioscience Research | Mount Kisco | New York | 10549 | — |
| Manhattan Behavioral Medicine | New York | New York | 10022 | — |
| Eastside Comprehensive Medical Center, LLC | New York | New York | 10128 | — |
| The Medical Research Network, LLC | New York | New York | 10128 | — |
| Fieve Clinical Research | New York | New York | 10168 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Carolina Clinical Trials, Inc. | Charleston | North Carolina | 29407 | — |
| New Hope Clinical Research Inc. | Charlotte | North Carolina | 28211 | — |
| Richard H. Weisler, MD, PA | Raleigh | North Carolina | 27609 | — |
| Neuro-Behavioral Clinical Research, Inc | Canton | Ohio | 44718 | — |
| Patient Priority Clinical Site, LLC | Cincinnati | Ohio | 45215 | — |
| The Ohio State University Department of Psychiatry | Columbus | Ohio | 43210 | — |
| Midwest Clinical Research Center LLC | Dayton | Ohio | 45417 | — |
| Charak Clinical Research Center | Garfield Heights | Ohio | 44125 | — |
| Lindner Center of Hope | Mason | Ohio | 45040 | — |
| Professional Psychiatric Services | Mason | Ohio | 45040 | — |
| IPS Research | Oklahoma City | Oklahoma | 73103 | — |
| Red River Medical Research Center, LLC | Oklahoma City | Oklahoma | 73112 | — |
| Sooner Clinical Research, Inc | Oklahoma City | Oklahoma | 73112 | — |
| Paradigm Research Professionals | Oklahoma City | Oklahoma | 73118 | — |
| Summit Research Network | Portland | Oregon | 97210 | — |
| Lehigh Center for Clinical Research | Allentown | Pennsylvania | 18104 | — |
| Suburban Research Associates | Media | Pennsylvania | 19063 | — |
| Keystone Clinical Studies, LLC | Norristown | Pennsylvania | 20006 | — |
| Coastal Carolina Research Center, Inc. | Mt. Pleasant | South Carolina | 29464 | — |
| Clinical Neuroscience Solutions, Inc | Memphis | Tennessee | 38119 | — |
| Research Strategies of Memphis, LLC | Memphis | Tennessee | 38119 | — |
| Donald J. Garcia, Jr., MD, PA | Austin | Texas | 78737 | — |
| Community Clinical Research, Inc. | Austin | Texas | 78754 | — |
| BioBehavioral Research of Austin | Austin | Texas | 78759 | — |
| Houston Clinical Trials, LLC | Bellaire | Texas | 77401 | — |
| Relaro Medical Trials | Dallas | Texas | 75243 | — |
| El Campo Clinical Trials | El Campo | Texas | 77347 | — |
| North Texas Clinical Trials | Fort Worth | Texas | 76104 | — |
| Earle Research | Houston | Texas | 77058 | — |
| Red Oak Psychiatry Associates, PA | Houston | Texas | 77090 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Family Psychiatry of The Wood | The Woodlands | Texas | 77381 | — |
| Grayline Clinical Drug Trials | Wichita Falls | Texas | 76309 | — |
| Psychiatric and Behavioral Solutions | Salt Lake City | Utah | 84105 | — |
| Pharmaceutical Research Associates, Inc | Salt Lake City | Utah | 84106 | — |
| Psychiatric Alliance of the Blue Ridge, Inc. | Charlottesville | Virginia | 22903 | — |
| NorthWest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Pacific Institute of Medical Sciences | Bothell | Washington | 98011 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03002077, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2020 · Synced Oct 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03002077 live on ClinicalTrials.gov.