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Completed Phase 2Phase 3 Interventional Results available

Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma

ClinicalTrials.gov ID: NCT03005418

Public ClinicalTrials.gov record NCT03005418. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 19, 2026, 5:36 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2/3 Study for the Evaluation of Safety and Efficacy of Humacyte's ATEV for Vascular Replacement or Reconstruction in Patients With Life or Limb-threatening Vascular Trauma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study evaluates the use of the Acellular Tissue Engineered Vessel (ATEV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery. There will be an extremity cohort and an torso cohort. All subjects will be implanted with an ATEV as an interposition vessel or bypass using standard vascular surgical techniques. There is no control arm.

Study identification

NCT ID
NCT03005418
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Humacyte, Inc.
Industry
Enrollment
72 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2018
Primary completion
Sep 18, 2023
Completion
May 14, 2026
Last update posted
Jul 28, 2026

2018 – 2026

United States locations

U.S. sites
27
U.S. states
13
U.S. cities
21
Facility City State ZIP Site status
Jacob Medical Center at UC San Diego La Jolla California 92037
Keck Hospital of University of Southern California (USC) Los Angeles California 90033
Cedars-Sinai Medical Cener Los Angeles California 90048
UCI Medical Center Orange California 92868
University California, Davis Sacramento California 95817
University of California San Diego (UCSD) Medical Center San Diego California 92103
Ernest E Moore Shock Trauma Center at Denver Health Denver Colorado 80204
UF Health Jacksonville Jacksonville Florida 32209
Jackson South Medical Center Miami Florida 33136
Ryder Trauma Center Miami Florida 33136
Tampa General Hospital Tampa Florida 33606
Grady Memorial Hospital Atlanta Georgia 30303
R Adams Cowley Baltimore Shock Trauma Baltimore Maryland 21201
Johns Hopkins Bayview Medical Center Baltimore Maryland 21224
Johns Hopkins Hospital Baltimore Maryland 21287
Mayo Clinic Rochester Minnesota 55905
Saint Louis University (SLU) St Louis Missouri 63110
Cooper University Hospital Camden New Jersey 08103
Rutgers New Jersey Medical School Newark New Jersey 07103
Duke University Hospital Durham North Carolina 27705
Atrium Health Wake Forest Baptist Medical Center Winston-Salem North Carolina 27157
Wake Forest School of Medicine Winston-Salem North Carolina 27157
Oregon Health & Science University Portland Oregon 97239
Penn Presbyterian Medical Center Philadelphia Pennsylvania 19104
Temple University Hospital Philadelphia Pennsylvania 19140
Vanderbilt University Medical Center Nashville Tennessee 37232
The University of Texas - Dell Medical School Austin Texas 78701

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03005418, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 28, 2026 · Synced Sep 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03005418 live on ClinicalTrials.gov.

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