Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy
Public ClinicalTrials.gov record NCT03007407. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of the Dual Immune Checkpoint Blockade With Durvalumab (MEDI4736) Plus Tremelimumab Following Palliative Hypofractionated Radiation in Patients With Microsatellite Stable (MSS) Metastatic Colorectal Cancer Progressing on Chemotherapy
Study identification
- NCT ID
- NCT03007407
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- NSABP Foundation Inc
- Network
- Enrollment
- 33 participants
Conditions and interventions
Conditions
Interventions
- durvalumab Drug
- Tremelimumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 30, 2017
- Primary completion
- Apr 17, 2019
- Completion
- Aug 8, 2019
- Last update posted
- Dec 4, 2022
2017 – 2019
United States locations
- U.S. sites
- 18
- U.S. states
- 6
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | — |
| Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06510 | — |
| Smilow Cancer Hospital Care Center at North Haven | North Haven | Connecticut | 06473 | — |
| UF Health Davis Cancer Pavilion and Shands Med Plaza | Gainesville | Florida | 32608 | — |
| UF Health Shands Cancer Hospital | Gainesville | Florida | 32608 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32610 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Florida Health Cancer Center at Orlando Health | Orlando | Florida | 32806 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Cancer Care Specialists of Central Illinois/Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Cancer Care Specialists of Central Illinois-Swansea | Swansea | Illinois | 62226 | — |
| Trinity Health Michigan | Ann Arbor | Michigan | 48106 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| St. Joseph Mercy-Brighton | Brighton | Michigan | 48114 | — |
| St. Joseph Mercy-Canton | Canton | Michigan | 48188 | — |
| St Joseph Mercy-Chelsea | Chelsea | Michigan | 48118 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03007407, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 4, 2022 · Synced Jun 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03007407 live on ClinicalTrials.gov.