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Completed Phase 1 Interventional

Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease

ClinicalTrials.gov ID: NCT03008161

Public ClinicalTrials.gov record NCT03008161. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:36 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Multiple Dose, Dose Escalation Study of NPT088 in Patients With Probable Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate the safety and tolerability of multiple doses of NPT088 in patients with mild to moderate probable Alzheimer's Disease. The study will also evaluate the pharmacokinetics, immunogenicity and exploratory pharmacodynamic characteristics of multiple doses of NPT088.

Study identification

NCT ID
NCT03008161
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Proclara Biosciences, Inc.
Industry
Enrollment
83 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2016
Primary completion
Feb 5, 2019
Completion
Feb 5, 2019
Last update posted
Aug 14, 2019

2016 – 2019

United States locations

U.S. sites
23
U.S. states
9
U.S. cities
23
Facility City State ZIP Site status
ATP Clinical Research, Inc. Costa Mesa California 92626
Neurology Center of North Orange County Fullerton California 92835
Collaborative Neuroscience Network Long Beach California 90806
Southern California Research Simi Valley California 93065
Associated Neurologists of Southern Connecticut Fairfield Connecticut 06824
JEM Research Institute Atlantis Florida 33462
Indago Research and Health Center Hialeah Florida 33012
Alzheimer's Research and Treatment Center Lake Worth Florida 33449
Miami Jewish Health Systems Miami Florida 33137
Medical Research Group of Central Florida Orange City Florida 32763
Compass Research Orlando Florida 32806
Progressive Medical Research Port Orange Florida 32137
Axiom Clinical Research Tampa Florida 33609
Compass-The Villages The Villages Florida 32162
Medical Research and Health Education Foundation Columbus Georgia 31909
NeuroStudies LLC Decatur Georgia 30033
Princeton Medical Institute Princeton New Jersey 08540
Neurological Associates of Albany Albany New York 12208
Integrative Clinical Trials, Inc. Brooklyn New York 11229
Alzheimer's Memory Center Charlotte North Carolina 28270
Lehigh Center for Clinical Research Allentown Pennsylvania 18104
Abington Neurological Associates, Ltd Willow Grove Pennsylvania 19090
Neurology Clinic, PC Cordova Tennessee 38018

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03008161, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 14, 2019 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03008161 live on ClinicalTrials.gov.

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