Study of the Efficacy and Safety of AMAG-423 (Digoxin Immune Fab) in Antepartum Subjects With Severe Preeclampsia
Public ClinicalTrials.gov record NCT03008616. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/3a, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Efficacy and Safety of AMAG-423, a Digoxin Immune Fab, in Antepartum Subjects With Severe Preeclampsia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates the use of AMAG-423 (Digoxin Immune Fab) in addition to expectant management in the treatment of severe preeclampsia as compared to placebo.
Study identification
- NCT ID
- NCT03008616
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 58 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 12, 2017 (Actual)
- Primary completion
- Aug 13, 2020 (Actual)
- Completion
- Aug 13, 2020 (Actual)
- Last update posted
- May 22, 2026
2017 – 2020
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama | Mobile | Alabama | 36604 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Children's Hospital Foundation Building | Louisville | Kentucky | 40202 | — |
| Louisiana State University Health Sciences Center in New Orleans | New Orleans | Louisiana | 70112 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Detroit Medical Center (DMC) | Detroit | Michigan | 48201 | — |
| University Of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| University Hospitals Case Medical Center-Case Western Reserve University (CWRU) | Cleveland | Ohio | 44106 | — |
| Regional Obstetrical Consultants | Chattanooga | Tennessee | 37403 | — |
| The University of Texas Medical Branch (UTMB) | Galveston | Texas | 77555 | — |
| Texas Children's Hospital/Baylor College of Medicine | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston (UTHSC-H) | Houston | Texas | 77303 | — |
| Baylor Scott & White Health | Temple | Texas | 76508 | — |
| University of Virginia School Of Medicine | Charlottesville | Virginia | 29208 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03008616, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 22, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03008616 live on ClinicalTrials.gov.