A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis
Public ClinicalTrials.gov record NCT03011892. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Dose-Ranging, Vehicle-Controlled and Triamcinolone 0.1% Cream-Controlled Study to Evaluate the Safety and Efficacy of INCB018424 Phosphate Cream Applied Topically to Adults With Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to establish the efficacy of each strength of ruxolitinib cream once daily (QD) or twice daily (BID) in participants with atopic dermatitis as compared with vehicle cream BID.
Study identification
- NCT ID
- NCT03011892
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 307 participants
Conditions and interventions
Conditions
Interventions
- Ruxolitinib 0.15% Cream QD Drug
- Ruxolitinib 0.5% Cream QD Drug
- Ruxolitinib 1.5% Cream QD Drug
- Ruxolitinib 1.5% Cream BID Drug
- Triamcinolone 0.1% Cream BID Drug
- Vehicle Cream BID Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2017 (Actual)
- Primary completion
- Jan 10, 2018 (Actual)
- Completion
- Mar 12, 2018 (Actual)
- Last update posted
- Apr 9, 2021
2017 – 2018
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB DERMATOLOGY, 2000 6th Avenue South | Birmingham | Alabama | 35233 | — |
| BURKE PHARMACEUTICAL RESEARCH, 601 W. Commerce | Bryant | Arkansas | 72022 | — |
| ENCINO RESEARCH CENTER, 16133 Ventura Blvd | Encino | California | 91436 | — |
| DERMATOLOGY RESEARCH ASSOCIATES,8930 South Sepulveda Blvd | Los Angeles | California | 90045 | — |
| DERMATOLOGY SPECIALISTS, INC, 3629 Vista Way | Oceanside | California | 92056 | — |
| INTEGRATED RESEARCH GROUP, INC, 4646 Brockton Avenue | Riverside | California | 92506 | — |
| SAN LUIS DERMATOLOGY AND LASER CLINIC, 15 Santa Rosa Street | San Luis Obispo | California | 93405 | — |
| NEW ENGLAND RESEARCH ASSOCIATES LLC, 5520 Park Avenue | Trumbull | Connecticut | 06611 | — |
| DS RESEARCH, 2241 Green Valley Road | New Albany | Indiana | 47150 | — |
| THE INDIANA CLINICAL TRIALS CENTER, 824 Edwards Drive | Plainfield | Indiana | 46168 | — |
| DERMRESEARCH, 1169 Eastern Parkway 2310 | Louisville | Kentucky | 40217 | — |
| DS RESEARCH, 3810 Springhurst Blvd | Louisville | Kentucky | 40241 | — |
| ACTIVMED PRACTICES & RESEARCH, INC, 138 Conant Street | Beverly | Massachusetts | 01915 | — |
| TUFTS MEDICAL CENTER, 800 Washington Street | Boston | Massachusetts | 02111 | — |
| HENRY FORD HOSPITAL, 3031 West Grand Blvd | Detroit | Michigan | 48202 | — |
| WASHINGTON UNIVERSITY - DERMATOLOGY, 4921 Parkview Place | St Louis | Missouri | 63110 | — |
| WASHINGTON UNIVERSITY - DERMATOLOGY, 969 Mason Road | St Louis | Missouri | 63141 | — |
| ACTIVMED PRACTICES AND RESEARCH, INC, 110 Corporate Drive | Portsmouth | New Hampshire | 03801 | — |
| HASSMAN RESEARCH INSTITUTE, LLC, 175 Cross Keys Road | Berlin | New Jersey | 08009 | — |
| DERMATOLOGY CONSULTING SERVICES, PLLC, 2444 North Main Street | High Point | North Carolina | 27262 | — |
| WAKE RESEARCH ASSOCIATES LLC, 3100 Duraleigh Road | Raleigh | North Carolina | 27612 | — |
| DERMATOLOGISTS OF GREATER COLUMBUS, 2359 East Main Street | Bexley | Ohio | 43209 | — |
| RAPID MEDICAL RESEARCH, INC, 3619 Park East Drive | Cleveland | Ohio | 44122 | — |
| CENTRAL SOONER RESEARCH, 900 North Porter | Norman | Oklahoma | 73071 | — |
| PARISH DERMATOLOGY, INC, 1845 Walnut Street | Philadelphia | Pennsylvania | 19103 | — |
| PEAK RESEARCH LLC, 2589 Washington Rd | Upper Saint Clair | Pennsylvania | 15241 | — |
| ARLINGTON RESEARCH CENTER, INC, 711 East Lamar Blvd | Arlington | Texas | 76011 | — |
| DERMRESEARCH INC., 8140 North Mopac Expressway | Austin | Texas | 78759 | — |
| J&S STUDIES, INC, 1710 Crescent Pointe Pkwy | College Station | Texas | 77845 | — |
| CENTER FOR CLINICAL STUDIES (CCS), 1401 Binz | Houston | Texas | 77004 | — |
| SUZANNE BRUCE AND ASSOCIATES, PA, 1900 St. James Place | Houston | Texas | 77056 | — |
| CLINICAL TRIALS OF TEXAS, INC, 7940 Floyd Curl Drive | San Antonio | Texas | 78229 | — |
| DERMATOLOGY CLINICAL RESEARCH CENTER OF SAN ANTONIO, 7810 Louis Pasteur | San Antonio | Texas | 78229 | — |
| CENTER FOR CLINICAL STUDIES, 451 North Texas Avenue | Webster | Texas | 77598 | — |
| CHARLOTTESVILLE DERMATOLOGY, 600 Peter Jefferson Parkway | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03011892, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 9, 2021 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03011892 live on ClinicalTrials.gov.