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Completed Phase 2 Interventional Results available

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

ClinicalTrials.gov ID: NCT03013543

Public ClinicalTrials.gov record NCT03013543. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Setmelanotide (RM-493) Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study was to determine the effect of setmelanotide (RM-493) on weight, hunger assessments, and other factors in participants with rare genetic disorders of obesity.

Study identification

NCT ID
NCT03013543
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Enrollment
213 participants

Conditions and interventions

Eligibility (public fields only)

Age range
6 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 9, 2017
Primary completion
Feb 28, 2022
Completion
Feb 28, 2022
Last update posted
Aug 17, 2023

2017 – 2022

United States locations

U.S. sites
43
U.S. states
24
U.S. cities
40
Facility City State ZIP Site status
Synexus Clinical Research US, Inc. - Simon Williamson Clinic, PC Birmingham Alabama 35211
Synexus Clinical Research US, Inc. - Phoenix Southeast Chandler Arizona 85224
Synexus Clinical Research US, Inc. - Central Arizona Medical Associates, PC Mesa Arizona 85206
Honor Health Research Institute Scottsdale Arizona 85258
Axis Clinical Trials-Downtown Los Angeles California 90017
Axis Clinical Trials Headquarters Los Angeles California 90036
San Diego Wake Research San Diego California 92108
Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora Colorado 80045
Division of Endocrinology and Diabetes Children's National Hospital Washington D.C. District of Columbia 20010
University of Florida College of Medicine Gainesville Florida 32610
AXIS South Florida Clinical Trials Hialeah Florida 33016
Florida Hospital Orlando Florida 32804
Synexus Clinical Research US, Inc. - St. Petersburg Pinellas Park Florida 33781
Synexus Clinical Research US, Inc. - Chicago Chicago Illinois 60602
Maine Medical Partners Portland Maine 04102
NIH Hatfield Clinical Research Center Bethesda Maryland 20892
Baystate Medical Center Springfield Massachusetts 01107
University of Michigan Medicine Ann Arbor Michigan 48105
Precision Medicine for Obesity Research: Gastroenterology & Hepatology Mayo Clinic Rochester Minnesota 55905
Washington University St. Louis St Louis Missouri 63110
Impact Clinical Trials Las Vegas Nevada 89106
AXIS New York Clinical Trials Brooklyn New York 11201
University at Buffalo Buffalo New York 14203
AXIS Clinical Trials New York New York 10022
Icahn School of Medicine at Mount Sinai New York New York 10025
Columbia University New York New York 10032
Duke University Medical Center Durham North Carolina 27705
Wake Research Inc. Raleigh North Carolina 27612
Synexus Clinical Research US, Inc. - Akron Akron Ohio 44311
Synexus Clinical Research US, Inc. - Cincinnati Cincinnati Ohio 45236
Synexus Clinical Research US, Inc. - Columbus Columbus Ohio 43016
Obesity Institute, Geisinger Clinic Danville Pennsylvania 17822
Childrens Hospital of Philadelphia Philadelphia Pennsylvania 19104
Synexus Clinical Research US, Inc. - Primary Care Associates, PC Anderson South Carolina 29621
Wake Research TN Chattanooga Tennessee 37421
Le Bonheur Children's Hospital Memphis Tennessee 38103
Vanderbilt University School of Medicine Nashville Tennessee 37212-3157
Baylor College of Medicine Houston Texas 77030
Synexus Clinical Research US, Inc. - Plano Plano Texas 75093
Synexus Clinical Research US, Inc. - San Antonio San Antonio Texas 78229
University of Utah Salt Lake City Utah 84132
Seattle Children's Research Institute Seattle Washington 98101
Marshfield Clinic Research Institute Marshfield Wisconsin 54449

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03013543, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 17, 2023 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03013543 live on ClinicalTrials.gov.

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