Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Terminated Not applicable Interventional Results available

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)

ClinicalTrials.gov ID: NCT03016975

Public ClinicalTrials.gov record NCT03016975. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Assess Transcatheter Mitral Valve Repair With Edwards Cardioband System and GDMT vs GDMT Alone in Patients With FMR and Heart Failure

Study identification

NCT ID
NCT03016975
Recruitment status
Terminated
Study type
Interventional
Phase
Not applicable
Lead sponsor
Edwards Lifesciences
Industry
Enrollment
12 participants

Conditions and interventions

Interventions

  • Edwards Cardioband System Device
  • Guideline Directed Medical Therapy Drug

Device · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2017
Primary completion
Jul 18, 2019
Completion
Sep 19, 2022
Last update posted
Nov 29, 2023

2017 – 2022

United States locations

U.S. sites
24
U.S. states
17
U.S. cities
21
Facility City State ZIP Site status
Cedars-Sinai Medical Center Los Angeles California 90048
Stanford University Palo Alto California 94304
University of Colorado Denver Aurora Colorado 80045
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010
Emory University Hospital Atlanta Georgia 30322
Northwestern University Chicago Illinois 60611
St. Vincent Heart Center Indianapolis Indiana 46290
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Henry Ford Hospital Detroit Michigan 48202
Morristown Medical Center Morristown New Jersey 07960
NYU Langone Health New York New York 10016
Columbia University Medical Center/New York Presbyterian Hospital New York New York 10032
Lenox Hill Hospital - Northwell Health New York New York 10075
St. Francis Hospital Roslyn New York 11576
Sanger Heart & Vascular Institute - Atrium Health Charlotte North Carolina 28203
The Cleveland Clinic Foundation Cleveland Ohio 44195
Providence Health &Services, Heart & Vascular Institute Portland Oregon 97225
Oregon Health & Science University Portland Oregon 97239
Pinnacle Health Harrisburg Pennsylvania 17101
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104
The University of Texas Health Science Center at Houston Houston Texas 77030
The Heart Hospital Baylor Plano Plano Texas 75093
Intermountain Medical Center Murray Utah 84107
University of Virginia Health System Charlottesville Virginia 22908

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03016975, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 29, 2023 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03016975 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →