Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)
Public ClinicalTrials.gov record NCT03018340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To assess the efficacy of pimavanserin compared to placebo when given adjunctively to a selective serotonin reuptake inhibitor (SSRI)/serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant as treatment of patients with Major Depressive Disorder (MDD) and an inadequate response to antidepressant therapy
Study identification
- NCT ID
- NCT03018340
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 207 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2016 (Actual)
- Primary completion
- Sep 2018 (Actual)
- Completion
- Oct 2018 (Actual)
- Last update posted
- Nov 14, 2019
2016 – 2018
United States locations
- U.S. sites
- 36
- U.S. states
- 20
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB | Birmingham | Alabama | 35294 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| Collaborative Neuroscience Network, LLC | Garden Grove | California | 92845 | — |
| Synergy San Diego | National City | California | 91950 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| Schuster Medical Research Institute | Sherman Oaks | California | 91403 | — |
| Viking Clinical Research | Temecula | California | 92591 | — |
| Collaborative Neuroscience Network, LLC | Torrance | California | 90502 | — |
| Pacific Clinical Research Medical Group | Upland | California | 91786 | — |
| Meridien Research | Bradenton | Florida | 34201 | — |
| CNS Health care (Jacksonville) | Jacksonville | Florida | 32256 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| CNS Health care (Orlando) | Orlando | Florida | 32801 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30329 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Alam Medical Research, INC | Chicago | Illinois | 60612 | — |
| Alexian Brothers Center for Psychiatric Research | Hoffman Estates | Illinois | 60169 | — |
| KUMC | Wichita | Kansas | 67214 | — |
| St. Louis Clinical Trials | St Louis | Missouri | 63141 | — |
| Altea Research | Las Vegas | Nevada | 89102 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Manhattan Behavioral Medicine | New York | New York | 10036 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| Neuro-Behavioral Clinical Research | Canton | Ohio | 44718 | — |
| IPS Research | Oklahoma City | Oklahoma | 73103 | — |
| Rivus Wellness & Research Institute | Oklahoma City | Oklahoma | 73112 | — |
| Summit Research Network (Oregon) | Portland | Oregon | 97210 | — |
| UPenn | Philadelphia | Pennsylvania | 19104 | — |
| BTC of Lincoln | Lincoln | Rhode Island | 02865 | — |
| Carolina Clinical Trials, Inc. | Charleston | South Carolina | 29407 | — |
| FutureSearch Trials of Dallas, L.P. | Dallas | Texas | 75231 | — |
| UTSW | Dallas | Texas | 75235 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Pillar Clinical Research | Richardson | Texas | 75080 | — |
| Ericksen Research & Development | Clinton | Utah | 84015 | — |
| IPC Research | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03018340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 14, 2019 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03018340 live on ClinicalTrials.gov.