A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)
Public ClinicalTrials.gov record NCT03033069. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/Day) as Monotherapy or as Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the safety, efficacy and tolerability of brexpiprazole (with placebo) as monotherapy or combination therapy with Zoloft (sertraline) in adults with PTSD.
Study identification
- NCT ID
- NCT03033069
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 336 participants
Conditions and interventions
Conditions
Interventions
- Brexpiprazole Drug
- Sertraline Drug
- Brexpiprazole Matching Placebo Drug
- Sertraline Matching Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 26, 2017 (Actual)
- Primary completion
- Nov 12, 2018 (Actual)
- Completion
- Nov 12, 2018 (Actual)
- Last update posted
- Dec 8, 2021
2017 – 2018
United States locations
- U.S. sites
- 54
- U.S. states
- 22
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site | Tuscaloosa | Alabama | 35404 | — |
| Investigational Site | Phoenix | Arizona | 85032 | — |
| Investigational Site | Little Rock | Arkansas | 72211 | — |
| Investigational Site | Rogers | Arkansas | 72758 | — |
| Investigational Site | Bellflower | California | 90706 | — |
| Investigational Site | Beverly Hills | California | 90210 | — |
| Investigational Site | Glendale | California | 91206 | — |
| Investigational Site | National City | California | 91950 | — |
| Investigational Site | Oceanside | California | 92054 | — |
| Investigational Site | Oceanside | California | 92056 | — |
| Investigational Site | Orange | California | 92868 | — |
| Investigational Site | Redlands | California | 92374 | — |
| Investigational Site | Riverside | California | 92506 | — |
| Investigational Site | San Diego | California | 92103 | — |
| Investigational Site | San Marcos | California | 92078 | — |
| Investigational Site | Torrance | California | 90502 | — |
| Investigational Site | Colorado Springs | Colorado | 80910 | — |
| Investigational Site | Bradenton | Florida | 34201 | — |
| Investigational Site | Fort Lauderdale | Florida | 33319 | — |
| Investigational Site | Fort Myers | Florida | 33912 | — |
| Investigational Site | Gainesville | Florida | 32607 | — |
| Investigational Site | Jacksonville | Florida | 32256 | — |
| Investigational Site | North Miami | Florida | 33161 | — |
| Investigational Site | Orlando | Florida | 32801 | — |
| Investigational Site | Orlando | Florida | 32806 | — |
| Investigational Site | Tampa | Florida | 33614 | — |
| Investigational Site | Atlanta | Georgia | 30341 | — |
| Investigational Site | Decatur | Georgia | 30030 | — |
| Investigational Site | Roswell | Georgia | 30076 | — |
| Investigational Site | Chicago | Illinois | 60640 | — |
| Investigational Site | St Louis | Missouri | 63141 | — |
| Investigational Site | Las Vegas | Nevada | 89102 | — |
| Investigational Site | Berlin | New Jersey | 08009 | — |
| Investigational Site | Princeton | New Jersey | 08540 | — |
| Investigational Site | Brooklyn | New York | 11235 | — |
| Investigational Site | Cedarhurst | New York | 11516 | — |
| Investigational Site | New York | New York | 10128 | — |
| Investigational Site | Rochester | New York | 14618 | — |
| Investigational Site | Charlotte | North Carolina | 28211 | — |
| Investigational Site | Raleigh | North Carolina | 27609 | — |
| Investigational Site | Cincinnati | Ohio | 45215 | — |
| Investigational Site | Oklahoma City | Oklahoma | 73103 | — |
| Investigational Site | Oklahoma City | Oklahoma | 73118 | — |
| Investigational Site | Portland | Oregon | 97214 | — |
| Investigational Site | Salem | Oregon | 97301 | — |
| Investigational Site | Media | Pennsylvania | 19063 | — |
| Investigational Site | Norristown | Pennsylvania | 19403 | — |
| Investigational Site | Lincoln | Rhode Island | 02865 | — |
| Investigational Site | Charleston | South Carolina | 29401 | — |
| Investigational Site | Memphis | Tennessee | 38119 | — |
| Investigational Site | Bellaire | Texas | 77401 | — |
| Investigational Site | San Antonio | Texas | 78229 | — |
| Investigational Site | Wichita Falls | Texas | 76309 | — |
| Investigational Site | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03033069, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2021 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03033069 live on ClinicalTrials.gov.