A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
Public ClinicalTrials.gov record NCT03033511. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Subjects With Extensive Stage Small Cell Lung Cancer (MERU)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, randomized, double-blind, placebo-controlled, multinational, and multicenter study to evaluate the efficacy of rovalpituzumab tesirine as maintenance therapy following first-line platinum-based chemotherapy.
Study identification
- NCT ID
- NCT03033511
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 748 participants
Conditions and interventions
Conditions
Interventions
- Placebo for dexamethasone Drug
- Placebo for rovalpituzumab tesirine Drug
- Rovalpituzumab tesirine Drug
- Dexamethasone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 7, 2017 (Actual)
- Primary completion
- Nov 20, 2019 (Actual)
- Completion
- Nov 20, 2019 (Actual)
- Last update posted
- Jul 29, 2021
2017 – 2019
United States locations
- U.S. sites
- 54
- U.S. states
- 28
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Institute /ID# 156699 | Huntsville | Alabama | 35805 | — |
| University of South Alabama /ID# 160975 | Mobile | Alabama | 36604-3302 | — |
| Highlands Oncology Group /ID# 156722 | Fayetteville | Arkansas | 72703-4005 | — |
| Marin Cancer Care /ID# 159207 | Greenbrae | California | 94904 | — |
| Ucsd /Id# 157764 | La Jolla | California | 92093 | — |
| LA Hem-Oncology Med Group /ID# 156717 | Los Angeles | California | 90017 | — |
| Palo Alto Veterans Institute for Research /ID# 203695 | Palo Alto | California | 94304-1207 | — |
| St Jude Hospital dba St Joseph /ID# 156526 | Santa Rosa | California | 95403 | — |
| Icri /Id# 157765 | Whittier | California | 90603 | — |
| Kaiser Permanente Lone Tree /ID# 159331 | Lone Tree | Colorado | 80124 | — |
| Christiana Care Health Service /ID# 159212 | Newark | Delaware | 19713 | — |
| Holy Cross Hospital /ID# 156716 | Fort Lauderdale | Florida | 33308 | — |
| University of Florida - Archer /ID# 155799 | Gainesville | Florida | 32610 | — |
| Memorial Cancer Institute /ID# 156673 | Hollywood | Florida | 33021-5421 | — |
| Memorial Cancer Institute /ID# 164052 | Hollywood | Florida | 33021-5421 | — |
| Cancer Specialists of North Florida - Southpoint /ID# 156595 | Jacksonville | Florida | 32256 | — |
| Georgia Cancer Center /ID# 201894 | Atlanta | Georgia | 30342 | — |
| Southeastern Regional Medical /ID# 163064 | Newnan | Georgia | 30265 | — |
| St. Luke's Mountain States Tumor Institute - Boise /ID# 156691 | Boise | Idaho | 83712 | — |
| NorthShore University HealthSystem - Evanston Hospital /ID# 156664 | Evanston | Illinois | 60201 | — |
| Ingalls Memorial Hosp /ID# 156685 | Harvey | Illinois | 60426 | — |
| Goshen Center for Cancer Care /ID# 156682 | Goshen | Indiana | 46526 | — |
| Ashland-Bellefonte Cancer Ctr /ID# 202901 | Ashland | Kentucky | 41101 | — |
| University of Louisville /ID# 156683 | Louisville | Kentucky | 40202 | — |
| Ochsner Clinic Foundation /ID# 159136 | Baton Rouge | Louisiana | 70836-6455 | — |
| Henry Ford Health System /ID# 156712 | Detroit | Michigan | 48202 | — |
| Sparrow Regional Cancer Center, Sparrow Health System /ID# 156590 | Lansing | Michigan | 48912 | — |
| Mayo Clinic - Rochester /ID# 160181 | Rochester | Minnesota | 55905-0001 | — |
| MidAmerica Division, Inc. /ID# 163530 | Kansas City | Missouri | 64132 | — |
| Billings Clinic /ID# 201788 | Billings | Montana | 59101-0733 | — |
| Nebraska Hematology Oncology /ID# 156534 | Lincoln | Nebraska | 68506 | — |
| MD Anderson Cancer Center at Cooper - Camden /ID# 156681 | Camden | New Jersey | 08103 | — |
| Northwell Health - Monter Cancer Center /ID# 159252 | Lake Success | New York | 11042 | — |
| Icahn School of Med Mt. Sinai /ID# 159210 | New York | New York | 10029 | — |
| Stony Brook University Hospital /ID# 159272 | Stony Brook | New York | 11794-8183 | — |
| Montefiore Medical Center /ID# 201845 | The Bronx | New York | 10461 | — |
| Duke University Medical Center /ID# 156706 | Durham | North Carolina | 27710-3000 | — |
| Cone Health /ID# 156689 | Greensboro | North Carolina | 27403 | — |
| Cone Health /ID# 163612 | Greensboro | North Carolina | 27403 | — |
| Eastern Carolina University /ID# 159264 | Greenville | North Carolina | 27834 | — |
| Gabrail Cancer Center Research /ID# 156667 | Canton | Ohio | 44718 | — |
| Kaiser Permanente, NW /ID# 201793 | Portland | Oregon | 97227 | — |
| Thomas Jefferson University /ID# 156719 | Philadelphia | Pennsylvania | 19107-4414 | — |
| VA Pittsburgh HealthcareSystem /ID# 159284 | Pittsburgh | Pennsylvania | 15240 | — |
| Rhode Island Hospital /ID# 160834 | Providence | Rhode Island | 02903 | — |
| Sarah Cannon Research Institute-Chattanooga /ID# 202933 | Chattanooga | Tennessee | 37404-1108 | — |
| Thompson Cancer Survival Ctr /ID# 202460 | Knoxville | Tennessee | 37916 | — |
| Tennessee Oncology-Nashville Centennial /ID# 161168 | Nashville | Tennessee | 37203-1632 | — |
| Univ Medical Ctr Brackenridge /ID# 155798 | Austin | Texas | 78701 | — |
| Parkland Health and Hosp Syste /ID# 170933 | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center /ID# 157848 | Dallas | Texas | 75390-7208 | — |
| Houston Methodist Hospital - Scurlock Tower /ID# 202323 | Houston | Texas | 77030 | — |
| Medical Oncology Associates /ID# 156715 | Spokane | Washington | 99208 | — |
| West Virginia Univ School Med /ID# 156687 | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 254 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03033511, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2021 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03033511 live on ClinicalTrials.gov.