ClinicalTrials.gov record
A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
ClinicalTrials.gov ID: NCT03038100
Public ClinicalTrials.gov record NCT03038100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Study of Atezolizumab Versus Placebo Administered in Combination With Paclitaxel, Carboplatin, and Bevacizumab to Patients With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase III, global, double-blind, 2-arm randomized study designed to compare the efficacy and safety of atezolizumab + paclitaxel + carboplatin + bevacizumab versus placebo + paclitaxel + carboplatin + bevacizumab. Study participants will have Stage 3 or 4 ovarian cancer (OC), fallopian tube cancer (FTC), or primary peritoneal cancer (PPC) with macroscopic residual disease postoperatively (i.e., after primary tumor reductive surgery) or who will undergo neoadjuvant therapy followed by interval surgery.
Study identification
- NCT ID
- NCT03038100
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,301 participants
Conditions and interventions
Interventions
- Paclitaxel Drug
- Carboplatin Drug
- Atezolizumab Drug
- Bevacizumab Drug
- Atezolizumab Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 8, 2017 (Actual)
- Primary completion
- Feb 8, 2022 (Actual)
- Completion
- Aug 12, 2022 (Actual)
- Last update posted
- Feb 17, 2023
2017 – 2022
United States locations
- U.S. sites
- 127
- U.S. states
- 41
- U.S. cities
- 104
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph'S Hospital & Medical Center | Phoenix | Arizona | 85013 | — |
| Arizona Oncology Associates, PC - HAL | Scottsdale | Arizona | 85258 | — |
| Arizona Oncology - HOPE Wilmot | Tucson | Arizona | 85710 | — |
| Moores Cancer Center at UC San Diego Health | La Jolla | California | 92093 | — |
| LAC + USC Medical Center | Los Angeles | California | 90033 | — |
| UCLA - School of Medicine | Los Angeles | California | 90095 | — |
| Kaiser Permanente - Oakland | Oakland | California | 94611 | — |
| The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange | Orange | California | 92868 | — |
| UC Irvine Medical Center | Orange | California | 92868 | — |
| Stanford University | Palo Alto | California | 94305 | — |
| Kaiser Permanente - Sacramento | Roseville | California | 95661 | — |
| Southern California Kaiser Permanente | San Diego | California | 92108 | — |
| California Pacific Medical Center Research Institute | San Francisco | California | 94115 | — |
| K. Permanente - San Fransisco | San Francisco | California | 94115 | — |
| University of California San Francisco Cancer Center | San Francisco | California | 94158 | — |
| Kaiser Permanente - Santa Clara | Santa Clara | California | 95051 | — |
| Olive View/Ucla Medical Center | Sylmar | California | 91342 | — |
| Kaiser Permanente - Walnut Creek | Walnut Creek | California | 94596 | — |
| University of Colorado Hospital - Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Eastern Connecticut Hematology and Oncology Associates; (ECHO) | Norwich | Connecticut | 06360 | — |
| Sylvester Comprehensive Cent. | Miami | Florida | 33136 | — |
| Miami Cancer Institute of Baptist Health, Inc. | Miami | Florida | 33176 | — |
| Sarasota Memorial Health Care System; Cancer Research Program | Sarasota | Florida | 34239 | — |
| Women's Cancer Associates | St. Petersburg | Florida | 33701 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Northeast Georgia Medical Center; Oncology Research Dept-5C | Gainesville | Georgia | 30501 | — |
| Women's Cancer Center | Honolulu | Hawaii | 96826 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Univ of Chicago | Chicago | Illinois | 60637 | — |
| Sudarshan K. Sharma, MD, Ltd. | Hinsdale | Illinois | 60521 | — |
| Parkview Research Center | Fort Wayne | Indiana | 46845 | — |
| St.Vincent Health System; Gynecologic Oncology | Indianapolis | Indiana | 46260 | — |
| University of Iowa Hospital & Clinic; Division of Hematology/Oncology | Iowa City | Iowa | 52242 | — |
| University of Kentucky; Gynecologic Oncology | Lexington | Kansas | 40536 | — |
| St. Elizabeth Edgewood; Cancer Care Center? for Account St. Elizabeth Edgewood | Edgewood | Kentucky | 41017 | — |
| Woman's Hospital | Baton Rouge | Louisiana | 70817 | — |
| Maine Medical Partners Women's Health; Gyn-Oncology | Scarborough | Maine | 04074 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Weinberg CA Inst Franklin Sq | Baltimore | Maryland | 21237 | — |
| Frederick Health Hospital | Frederick | Maryland | 21701 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| Sanford Health Bemidji | Bemidji | Minnesota | 56601 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Metro-Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Minnesota Oncology Hematology Woodbury | Woodbury | Minnesota | 55125 | — |
| St. Dominic-Jackson Memorial Hospital | Jackson | Mississippi | 39216 | — |
| Washington University School of Medicine; Dept of Medicine/Div of Medical Oncology | St Louis | Missouri | 63108 | — |
| Billings Clinic; Cancer Center | Billings | Montana | 59101 | — |
| Community Cancer Care | Missoula | Montana | 59804 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-0600 | — |
| Women's Cancer Center | Las Vegas | Nevada | 89106 | — |
| Center of Hope | Reno | Nevada | 89511 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| MSK @Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Cooper Health System; MD Anderson Cancer Center | Camden | New Jersey | 08103 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Memorial Sloan Kettering Cancer Center; MSK Monmouth | Middletown | New Jersey | 07748 | — |
| Jersey Shore Med Ctr; OB/GYN | Neptune City | New Jersey | 07753 | — |
| Holy Name Hospital | Teaneck | New Jersey | 07666 | — |
| Southwest Gynecologic Oncology Associates, Inc. | Albuquerque | New Mexico | 87106 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Womens Cancer Care Association | Albany | New York | 12208 | — |
| New York Presbyterian Queens | Flushing | New York | 11355 | — |
| Northwell Health; Monter Cancer Center | Lake Success | New York | 11042 | — |
| New York Univ Medical Center; Obstetrics & Gynecolog | New York | New York | 10016 | — |
| Mount Sinai Downtown Chelsea Centre | New York | New York | 10029-6574 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 11101 | — |
| Memorial Sloan-Kettering CC | Rockville Centre | New York | 11570 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Novant Health Presbyterain Medical Center | Charlotte | North Carolina | 28204 | — |
| Duke Medical Center | Durham | North Carolina | 27710 | — |
| Forsythe Memorial Hospital Inc., dba Novant Health Oncology Specialists | Winston-Salem | North Carolina | 27103 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Sanford Health Bismarck | Bismarck | North Dakota | 58506 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58102 | — |
| University of Cincinnati | Cincinnati | Ohio | 45203-0542 | — |
| Cleveland Clinic | Cleveland | Ohio | 44106 | — |
| Univ Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Fairview Hospital; Cleveland Clinic Cancer Center | Cleveland | Ohio | 44111 | — |
| Columbus NCORP | Columbus | Ohio | 43125 | — |
| Ohio State University, Arthur James Cancer Hospital | Columbus | Ohio | 43210 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| University of Oklahoma; Stephenson Oklahoma Canc Ctr | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Cancer Specialists and Research Institute | Tulsa | Oklahoma | 74146 | — |
| Oncology Associates of Oregon, P.C.; Willamette Valley Cancer Institute | Springfield | Oregon | 97477 | — |
| Northwest Cancer Specialists, P.C. | Tigard | Oregon | 97223 | — |
| University of Pennsylvania Health System; Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Magee-Woman's Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Abington Mem Hosp-Abington; Rose. Can Ctr,Gyn Onc Ins | Willow Grove | Pennsylvania | 19090 | — |
| WellSpan Gynecologic Oncology | York | Pennsylvania | 17403 | — |
| Women & Infants Hospital | Providence | Rhode Island | 02905 | — |
| Bon Secours - St. Francis Hospital | Greenville | South Carolina | 29607 | — |
| Monument Health Rapid City Hospital, Inc. | Rapid City | South Dakota | 57701 | — |
| Sanford Health System | Sioux Falls | South Dakota | 57105 | — |
| Dell Seton Medical Center at UT-Seton Infusion Center; Research Department | Austin | Texas | 78701 | — |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | — |
| Texas Oncology | Bedford | Texas | 76022 | — |
| UT Southwestern Medical Center at Dallas; Department of Pathology | Dallas | Texas | 75390-9016 | — |
| Texas Oncology, P.A. - Fort Worth | Fort Worth | Texas | 76104 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Rocky Mountain Cancer Centers, LLP | Irving | Texas | 75063 | — |
| Texas Oncology San Antonio Medical Center | San Antonio | Texas | 78240 | — |
| Texas Oncology, P.A. | The Woodlands | Texas | 77060 | — |
| Texas Oncology- Northeast Texas | Tyler | Texas | 75702 | — |
| Huntsman Cancer Institute; Oncology | Salt Lake City | Utah | 84112 | — |
| Dixie Medical Center | St. George | Utah | 84790 | — |
| University of Virginia | Charlottesville | Virginia | 22906 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Henrico Doctors' Hospital - Forest | Richmond | Virginia | 23229 | — |
| Shenandoah Oncology Associates | Winchester | Virginia | 22601 | — |
| University of Washington Seattle Cancer Care Alliance | Seattle | Washington | 98195 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| DN Greenwald Center | Mukwonago | Wisconsin | 53149 | — |
| Aspirus Regional Cancer Center | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 141 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03038100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 17, 2023 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03038100 live on ClinicalTrials.gov.