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Completed Phase 2 Interventional Results available

Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration

ClinicalTrials.gov ID: NCT03038880

Public ClinicalTrials.gov record NCT03038880. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

STAIRWAY: Simultaneous Blockade of Angiopoietin-2 and VEGF-A With the Bispecific Antibody RO6867461 (RG7716) for Extended Durability in the Treatment of Neovascular Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This was a Phase II, multicenter, randomized, active comparator-controlled, 52-week study to investigate the efficacy, safety and pharmacokinetics of faricimab (RO6867461; RG7716) administered with extended dosing regimens in treatment-naive participants with neovascular age related macular degeneration (nAMD). Only one eye was chosen as the study eye.

Study identification

NCT ID
NCT03038880
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
76 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 27, 2017 (Actual)
Primary completion
Jan 11, 2018 (Actual)
Completion
Mar 29, 2018 (Actual)
Last update posted
Jan 5, 2021

2017 – 2018

United States locations

U.S. sites
25
U.S. states
16
U.S. cities
25
Facility City State ZIP Site status
Retinal Consultants of Arizona Phoenix Arizona 85053 —
Retina Associates Southwest PC Tucson Arizona 85704 —
California Retina Consultants Bakersfield California 93309 —
Retinal Diagnostic Center Campbell California 95008 —
Retina Consultants of Southern Colorado PC; Clinical Research Department Colorado Springs Colorado 80909-1183 —
Rand Eye Deerfield Beach Florida 33064 —
Florida Eye Associates Melbourne Florida 32901 —
Retina Vitreous Assoc of FL St. Petersburg Florida 33711 —
Southern Vitreoretinal Assoc Tallahassee Florida 32308 —
Southeast Retina Center Augusta Georgia 30909 —
Midwest Eye Institute Indianapolis Indiana 46290 —
Wolfe Eye Clinic West Des Moines Iowa 50266 —
The Retina Care Center Baltimore Maryland 21209 —
Vitreo Retinal Surgery Minneapolis Minnesota 55435 —
Sierra Eye Associates Reno Nevada 89502 —
Eye Associates of New Mexico Albuquerque New Mexico 87109 —
Vitreoretinal Consultants Great Neck New York 11021 —
Oregon Retina, LLP Eugene Oregon 97401 —
Retina Northwest Portland Oregon 97221 —
Charles Retina Institute Germantown Tennessee 38138 —
Retina Res Institute of Texas Abilene Texas 79606 —
Texas Retina Associates Arlington Texas 76012 —
Retina Research Center Austin Texas 78750 —
Strategic Clinical Research Group, LLC Willow Park Texas 76087 —
Retina Associates of Utah Salt Lake City Utah 84107 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03038880, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 5, 2021 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03038880 live on ClinicalTrials.gov.

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