Evaluation of an Alternative Injection Paradigm for OnabotulinumtoxinA (BOTOX®) in the Treatment of Overactive Bladder in Patients With Urinary Incontinence
Public ClinicalTrials.gov record NCT03052764. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate an Alternative Injection Paradigm for OnabotulinumtoxinA (BOTOX®) in the Treatment of Overactive Bladder in Patients With Urinary Incontinence (LO-BOT)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of onabotulinumtoxinA 100 U (BOTOX®), compared to placebo, when injected into the bladder using an alternative injection paradigm in reducing the number of daily urinary incontinence episodes in patients with overactive bladder (OAB) and urinary incontinence whose symptoms have not been adequately managed with an anticholinergic.
Study identification
- NCT ID
- NCT03052764
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 12, 2016 (Actual)
- Primary completion
- Dec 10, 2018 (Actual)
- Completion
- Dec 10, 2018 (Actual)
- Last update posted
- Dec 24, 2019
2016 – 2018
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Orange County Urology Associates | Laguna Hills | California | 92653 | — |
| Tower Urology | Los Angeles | California | 90048 | — |
| University of California, Irvine Medical Center | Orange | California | 92868 | — |
| Genitourinary Surgical Consultants | Denver | Colorado | 80220 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32204 | — |
| PMG Research of Christie Clinic | Champaign | Illinois | 81820 | — |
| Deaconess Clinic, Inc. | Evansville | Indiana | 47113 | — |
| Women's Health Advantage | Fort Wayne | Indiana | 46825 | — |
| Urogynecology Associates | Indianapolis | Indiana | 46062 | — |
| Urology of Indiana | Noblesville | Indiana | 46062 | — |
| Iowa Clinic | West Des Moines | Iowa | 50266 | — |
| Regional Urology | Shreveport | Louisiana | 71106 | — |
| Chesapeake Urology | Owings Mills | Maryland | 21117 | — |
| Beyer Research | Kalamazoo | Michigan | 49009 | — |
| Michigan Institute of Urology, P.C. | Troy | Michigan | 48084 | — |
| Adult and Pediatric Urology | Omaha | Nebraska | 68114 | — |
| Premier Urology LLC | Edison | New Jersey | 08837 | — |
| Western New York Urology Associates | Cheektowaga | New York | 14225 | — |
| Manhattan Medical Research | New York | New York | 10016 | — |
| Advanced Urology Centers of NY A division of IMP | Plainview | New York | 11803 | — |
| Premier Medical Group of the Hudson Valley | Poughkeepsie | New York | 12601 | — |
| Alliance Urology Specialists | Greensboro | North Carolina | 27403 | — |
| Sandhills Medical Center | Hamlet | North Carolina | 28345 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Urologic Consultants of Southeastern Pennsylvania | Bala-Cynwyd | Pennsylvania | 19004 | — |
| Center for Pelvic Health | Franklin | Tennessee | 37067 | — |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | — |
| Virginia Urology | Richmond | Virginia | 23230 | — |
| Virginia Urology Center | Richmond | Virginia | 23235 | — |
| Urology of Virginia | Virginia Beach | Virginia | 23462 | — |
| Integrity Medical Research, LLC | Mountlake Terrace | Washington | 98043 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03052764, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 24, 2019 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03052764 live on ClinicalTrials.gov.