An Active-Controlled Early Phase Study of Elpipodect (MK-8189) in Adults With Schizophrenia (MK-8189-005)
Public ClinicalTrials.gov record NCT03055338. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Efficacy and Safety of MK-8189 Using Risperidone as an Active Control in Subjects Experiencing an Acute Episode of Schizophrenia
Study identification
- NCT ID
- NCT03055338
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 224 participants
Conditions and interventions
Conditions
Interventions
- Elpipodect Drug
- Placebo matching MK-8189 Drug
- Placebo matching risperidone Drug
- Risperidone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 7, 2017
- Primary completion
- Jan 8, 2018
- Completion
- Jan 8, 2018
- Last update posted
- Apr 28, 2026
2017 – 2018
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Woodland International Research Group, LLC ( Site 0001) | Little Rock | Arkansas | 72211 | — |
| Woodland Research Northwest, LLC ( Site 0014) | Rogers | Arkansas | 72758 | — |
| CITRIALS ( Site 0013) | Bellflower | California | 90706 | — |
| Comprehensive Clinical Development ( Site 0049) | Cerritos | California | 90703 | — |
| Collaborative Neuroscience Network, LLC ( Site 0057) | Garden Grove | California | 92845 | — |
| Behavioral Research Specialists, LLC ( Site 0006) | Glendale | California | 91206 | — |
| Synergy East ( Site 0003) | Lemon Grove | California | 91945 | — |
| NRC Research Institute ( Site 0043) | Orange | California | 92868 | — |
| CNRI - Los Angeles, LLC ( Site 0026) | Pico Rivera | California | 90660 | — |
| Artemis Institute for Clinical Research ( Site 0027) | San Diego | California | 92103 | — |
| Schuster Medical Research Institute ( Site 0032) | Sherman Oaks | California | 91403 | — |
| Collaborative Neuroscience Network, LLC ( Site 0046) | Torrance | California | 90502 | — |
| Larkin Community Hospital Behavioral Health Services ( Site 0020) | Hollywood | Florida | 33021 | — |
| Clinical Research Centers of America, LLC ( Site 0038) | Oakland Park | Florida | 33334 | — |
| Aspire Health Partners ( Site 0016) | Orlando | Florida | 32810 | — |
| Radiant Research - Atlanta ( Site 0008) | Atlanta | Georgia | 30328 | — |
| Atlanta Center For Medical Research ( Site 0056) | Atlanta | Georgia | 30331 | — |
| Alexian Center for Psychiatric Research ( Site 0015) | Hoffman Estates | Illinois | 60169 | — |
| Lake Charles Clinical Trials, LLC ( Site 0040) | Lake Charles | Louisiana | 70629 | — |
| CBH Health, LLC ( Site 0022) | Gaithersburg | Maryland | 20877 | — |
| Precise Research Centers ( Site 0018) | Flowood | Mississippi | 39232 | — |
| Psych Care Consultants Research ( Site 0025) | St Louis | Missouri | 63128 | — |
| St. Louis Clinical Trials, LLC ( Site 0012) | St Louis | Missouri | 63141 | — |
| Altea Research Institute ( Site 0017) | Las Vegas | Nevada | 89102 | — |
| Radiant Research -CliniLabs ( Site 0037) | New York | New York | 10019 | — |
| Midwest Clinical Research Unit ( Site 0041) | Dayton | Ohio | 45417 | — |
| InSite Clinical Research ( Site 0033) | DeSoto | Texas | 75115 | — |
| Pillar Clinical Research, LLC ( Site 0004) | Richardson | Texas | 75080 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03055338, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2026 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03055338 live on ClinicalTrials.gov.