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Completed Phase 1 Interventional

Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's Disease

ClinicalTrials.gov ID: NCT03065192

Public ClinicalTrials.gov record NCT03065192. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 2:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label Safety and Efficacy Study of VY-AADC01 Administered by MRI-Guided Convective Infusion Using a Posterior Trajectory Into the Putamen of Participants With Parkinson's Disease With Fluctuating Responses to Levodopa

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Safety and efficacy of AADC gene transfer in participants with Parkinson's disease.

Study identification

NCT ID
NCT03065192
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Neurocrine Biosciences
Industry
Enrollment
16 participants

Conditions and interventions

Eligibility (public fields only)

Age range
40 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 10, 2017
Primary completion
Aug 9, 2021
Completion
Aug 9, 2021
Last update posted
Mar 20, 2022

2017 – 2021

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
University of California, San Francisco (UCSF) San Francisco California 94143
Emory University Atlanta Georgia 30322
Ohio State University (OSU) Columbus Ohio 43210
University of Pittsburgh Medical Center (UPMC) Pittsburgh Pennsylvania 15213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03065192, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 20, 2022 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03065192 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →