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Completed Phase 3 Interventional Results available

A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients

ClinicalTrials.gov ID: NCT03066804

Public ClinicalTrials.gov record NCT03066804. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 7:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 24-week, Randomized, Double-blind, Multi-center, Parallel LCZ696 on NT-proBNP, Exercise Capacity, Symptoms and Safety Compared to Individualized Medical Management of Comorbidities in Patients With Heart Failure and Preserved Ejection Fraction

Study identification

NCT ID
NCT03066804
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
2,572 participants

Conditions and interventions

Interventions

  • sacubitril/valsartan Drug
  • Enalapril Drug
  • Valsartan Drug
  • Placebo to match sacubitril/valsartan Drug
  • Placebo to match enalapril Drug
  • Placebo to match valsartan Drug

Drug

Eligibility (public fields only)

Age range
45 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 21, 2017
Primary completion
Oct 27, 2019
Completion
Oct 27, 2019
Last update posted
Oct 10, 2021

2017 – 2019

United States locations

U.S. sites
32
U.S. states
19
U.S. cities
32
Facility City State ZIP Site status
Novartis Investigative Site Andalusia Alabama 36420
Novartis Investigative Site Mobile Alabama 36608
Novartis Investigative Site Beverly Hills California 90211
Novartis Investigative Site Long Beach California 90813
Novartis Investigative Site Santa Ana California 92704
Novartis Investigative Site Sylmar California 91342
Novartis Investigative Site Aurora Colorado 80045
Novartis Investigative Site Stamford Connecticut 06905
Novartis Investigative Site Bradenton Florida 34209
Novartis Investigative Site Gainesville Florida 32608
Novartis Investigative Site Hollywood Florida 33312
Novartis Investigative Site Miami Florida 33133
Novartis Investigative Site Port Orange Florida 32127
Novartis Investigative Site Thomasville Georgia 31792
Novartis Investigative Site Arlington Heights Illinois 60004
Novartis Investigative Site Alexandria Louisiana 71301
Novartis Investigative Site Chalmette Louisiana 70043
Novartis Investigative Site Houma Louisiana 70360
Novartis Investigative Site Boston Massachusetts 02114
Novartis Investigative Site Lincoln Nebraska 68526
Novartis Investigative Site Omaha Nebraska 68114
Novartis Investigative Site Rochester New York 14621
Novartis Investigative Site Marion Ohio 43302
Novartis Investigative Site Corvallis Oregon 97330
Novartis Investigative Site Abington Pennsylvania 19001
Novartis Investigative Site Sioux Falls South Dakota 57104
Novartis Investigative Site Jackson Tennessee 38301
Novartis Investigative Site Dallas Texas 75234
Novartis Investigative Site Lufkin Texas 75904
Novartis Investigative Site Tomball Texas 77375
Novartis Investigative Site Falls Church Virginia 22042
Novartis Investigative Site Seattle Washington 98122

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 348 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03066804, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 10, 2021 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03066804 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →