Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)
Public ClinicalTrials.gov record NCT03068754. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double Blind, Placebo Controlled Study to Assess the Efficacy and Safety of H.P. Acthar® Gel in the Treatment of Subjects With Amyotrophic Lateral Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
About 213 people with ALS will participate in this study. There will be locations in North and South America. During the first part, participants will be randomly assigned to a group (like by flipping a coin). Out of every 3: * 2 will get the study drug * 1 will get a look-alike with no drug in it (placebo) During the second part, everyone will get the study drug. Participation will help doctors find out if Acthar can help or slow down the symptoms of ALS better than placebo.
Study identification
- NCT ID
- NCT03068754
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 143 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2017 (Actual)
- Primary completion
- Nov 25, 2019 (Actual)
- Completion
- Nov 25, 2019 (Actual)
- Last update posted
- Oct 14, 2020
2017 – 2019
United States locations
- U.S. sites
- 39
- U.S. states
- 24
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neuromuscular Research Center | Phoenix | Arizona | 85028 | — |
| Mayo Clinic - Arizona | Scottsdale | Arizona | 85259 | — |
| University of California San Diego | La Jolla | California | 92037 | — |
| Loma Linda University Health System, Department of Neurology | Loma Linda | California | 92354 | — |
| Keck School of Medicine, University of Southern California | Los Angeles | California | 90033 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Colorado Springs Neurological Associates | Colorado Springs | Colorado | 80907 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| University of Florida - McKnight Brain Institute | Gainesville | Florida | 32611 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Indiana University-Neuroscience Center of Excellence/Goodman Hall | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536 | — |
| John Hopkins Outpatient Center | Baltimore | Maryland | 21287 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| Mercy Health- Saint Mary's | Grand Rapids | Michigan | 49503 | — |
| Neurology Associates | Lincoln | Nebraska | 68510 | — |
| University of Nebraska Medical Center - Physicians Clinical Neurosciences Center | Omaha | Nebraska | 68198 | — |
| Las Vegas Clinic | Las Vegas | Nevada | 89145 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Columbia Presbyterian Hospital | New York | New York | 10032 | — |
| Providence ALS Center | Portland | Oregon | 97213 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Wesley Neurology Clinic | Cordova | Tennessee | 38018 | — |
| Austin Neuromuscular Center | Austin | Texas | 78756 | — |
| Texas Neurology, P.A. | Dallas | Texas | 75214 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| University of Vermont Medical Center | Colchester | Vermont | 05401 | — |
| VCU Medical Center | Richmond | Virginia | 23298 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
| Medical College of Wisconsin/Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03068754, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2020 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03068754 live on ClinicalTrials.gov.