Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects
Public ClinicalTrials.gov record NCT03073967. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open Label, Multi-center, Comparative Trial, to Assess the Efficacy and Safety of Pritelivir for the Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects (PRIOH-1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Randomized, open-label, multi-center, comparative trial to assess the efficacy and safety in immunocompromised subjects with acyclovir resistant or acyclovir susceptible mucocutaneous HSV infection, treated with pritelivir 100 mg once daily (following a loading dose of 400 mg as first dose to rapidly reach steady-state plasma concentration) or investigators choice, which can be either foscarnet 40 mg/kg every 8 hours or 60 mg/kg every 12 hours, or Cidofovir iv 5 mg/kg body weight given once weekly, or Cidofovir 1% or 3% topical applied 2 to 4 times daily, or Imiquimod 5% topical 3 times per week) (provided the drug is nationally approved).
Study identification
- NCT ID
- NCT03073967
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 158 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 8, 2017 (Actual)
- Primary completion
- Aug 15, 2025 (Actual)
- Completion
- Nov 11, 2025 (Actual)
- Last update posted
- Jun 12, 2026
2017 – 2025
United States locations
- U.S. sites
- 33
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | — |
| Metro Infectious Disease Consultants, LLC - Huntsville | Huntsville | Alabama | 35801 | — |
| University of South Alabama | Mobile | Alabama | 36604 | — |
| University Arizona - Department of Medicine Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| City of Hope | Duarte | California | 91010 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, Division of Infectious Diseases | Sacramento | California | 95817 | — |
| Midland Florida Clinical Research Center, LLC | DeLand | Florida | 32720 | — |
| Midway Immunology and Research Center (MIRC) | Ft. Pierce | Florida | 34982 | — |
| University of Florida (UF) - Division of Infectious Disease | Gainesville | Florida | 32610 | — |
| Links Clinical Trials | Miami | Florida | 33176 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Emory Hospital Midtown Infectious Disease Clinic | Atlanta | Georgia | 30308 | — |
| Metro Infectious Disease Consultants - Atlanta | Decatur | Georgia | 30033 | — |
| Metro Infectious Disease Consultants, LLC | Burr Ridge | Illinois | 60527 | — |
| Department of Medicine J. H. Stroger Hospital of Cook County | Chicago | Illinois | 60612 | — |
| LSU Health Baton Rouge Pulmonary Clinic | Baton Rouge | Louisiana | 70809 | — |
| Tulane University - School of Medicine | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Lee's Summit MO United States 64086 | Lee's Summit | Missouri | 64086 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Rutgers Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Kings Country Hospital Center | Brooklyn | New York | 11203 | — |
| David H. Koch Center at Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | — |
| Duke University Medical Center - Division of Infectious Diseases | Durham | North Carolina | 27710 | — |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03073967, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 12, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03073967 live on ClinicalTrials.gov.